Detection of new mutation disease in man and mouse

M. Grompe, R. A. Gibbs, J. S. Chamberlain, C. T. Caskey

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Recent developments in molecular biology technology have greatly facilitated the methods for detection of mutations responsible for genetic disorders in both humans and animals. In this article we review some of these new methods and present a diagnostic algorithm that facilitates the routine and rapid diagnosis of any genetic disorder for which the defective gene has been isolated.

Original languageEnglish (US)
Pages (from-to)511-521
Number of pages11
JournalMolecular Biology and Medicine
Issue number6
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Molecular Biology


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