Detection of new mutation disease in man and mouse

Markus Grompe, R. A. Gibbs, J. S. Chamberlain, C. T. Caskey

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Recent developments in molecular biology technology have greatly facilitated the methods for detection of mutations responsible for genetic disorders in both humans and animals. In this article we review some of these new methods and present a diagnostic algorithm that facilitates the routine and rapid diagnosis of any genetic disorder for which the defective gene has been isolated.

Original languageEnglish (US)
Pages (from-to)511-521
Number of pages11
JournalMolecular Biology and Medicine
Volume6
Issue number6
StatePublished - 1989
Externally publishedYes

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Inborn Genetic Diseases
Mutation
Molecular Biology
Technology
Genes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Molecular Biology

Cite this

Grompe, M., Gibbs, R. A., Chamberlain, J. S., & Caskey, C. T. (1989). Detection of new mutation disease in man and mouse. Molecular Biology and Medicine, 6(6), 511-521.

Detection of new mutation disease in man and mouse. / Grompe, Markus; Gibbs, R. A.; Chamberlain, J. S.; Caskey, C. T.

In: Molecular Biology and Medicine, Vol. 6, No. 6, 1989, p. 511-521.

Research output: Contribution to journalArticle

Grompe, M, Gibbs, RA, Chamberlain, JS & Caskey, CT 1989, 'Detection of new mutation disease in man and mouse', Molecular Biology and Medicine, vol. 6, no. 6, pp. 511-521.
Grompe M, Gibbs RA, Chamberlain JS, Caskey CT. Detection of new mutation disease in man and mouse. Molecular Biology and Medicine. 1989;6(6):511-521.
Grompe, Markus ; Gibbs, R. A. ; Chamberlain, J. S. ; Caskey, C. T. / Detection of new mutation disease in man and mouse. In: Molecular Biology and Medicine. 1989 ; Vol. 6, No. 6. pp. 511-521.
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