Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography

Ruikang K. Wang, Lin An, Peter Francis, David J. Wilson

Research output: Contribution to journalArticle

254 Scopus citations

Abstract

We demonstrate the depth-resolved and detailed ocular perfusion maps within retina and choroid can be obtained from an ultrahigh sensitive optical microangiography (OMAG). As opposed to the conventional OMAG, we apply the OMAG algorithm along the slow scanning axis to achieve the ultrahigh sensitive imaging to the slow flows within capillaries. We use an 840 nm system operating at an imaging rate of 400 frames/s that requires 3 s to complete one 3D scan of ̃3×3 mm2 area on retina. We show the superior imaging performance of OMAG to provide functional images of capillary level microcirculation at different land-marked depths within retina and choroid that correlate well with the standard retinal pathology.

Original languageEnglish (US)
Pages (from-to)1467-1469
Number of pages3
JournalOptics Letters
Volume35
Issue number9
DOIs
StatePublished - May 1 2010

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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