Depression: Cause or Complication of Cognitive Decline?

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Depression may be a risk factor, prodrome, correlate or outcome of dementia. Proposed pathways linking depression with dementia include vascular disease, hippocampal atrophy, and proinflammatory changes. Depression is neither a normal nor expected development in old age, but the prevalence increases with increasing burden of medical illness in the older patient. New depression in old age often portends development of dementia.

    Original languageEnglish (US)
    Title of host publicationDementia
    PublisherWiley Blackwell
    Pages67-76
    Number of pages10
    ISBN (Electronic)9781118656082
    ISBN (Print)9780470674246
    DOIs
    StatePublished - Oct 28 2013

    Keywords

    • Alzheimer's disease
    • Antidepressant
    • Apathy
    • Cortisol
    • Dementia
    • Depression
    • Pseudodementia
    • Psychostimulant
    • Suicide
    • Vascular

    ASJC Scopus subject areas

    • Medicine(all)

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