Depression: Cause or Complication of Cognitive Decline?

David Mansoor, Sahana Misra, Linda Ganzini

    Research output: Chapter in Book/Report/Conference proceedingChapter


    Depression may be a risk factor, prodrome, correlate or outcome of dementia. Proposed pathways linking depression with dementia include vascular disease, hippocampal atrophy, and proinflammatory changes. Depression is neither a normal nor expected development in old age, but the prevalence increases with increasing burden of medical illness in the older patient. New depression in old age often portends development of dementia.

    Original languageEnglish (US)
    Title of host publicationDementia
    PublisherWiley Blackwell
    Number of pages10
    ISBN (Electronic)9781118656082
    ISBN (Print)9780470674246
    StatePublished - Oct 28 2013


    • Alzheimer's disease
    • Antidepressant
    • Apathy
    • Cortisol
    • Dementia
    • Depression
    • Pseudodementia
    • Psychostimulant
    • Suicide
    • Vascular

    ASJC Scopus subject areas

    • Medicine(all)

    Fingerprint Dive into the research topics of 'Depression: Cause or Complication of Cognitive Decline?'. Together they form a unique fingerprint.

    Cite this