Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method

An in vitro validation study

Muhammad Ashraf, Xiao Kui Li, Monica T. Young, Amariek J. Jensen, James Pemberton, Ling Hui, Peter Lysyansky, Zvi Friedman, Byung Park, David Sahn

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective. Normal left ventricular contraction involves a twisting component that helps augment stroke volume, the unwinding of which also very usefully contributes to early diastolic filling. Abnormalities of cardiac twist have been related to abnormal cardiac function. We sought to quantify the twisting action using a new sonographically based angle-independent motion-detecting echo method. Methods. A twist model was developed with a variable-speed motor to rotate a wheel in water bath. A freshly harvested pig heart was mounted on it as a twist phantom. Short axis views were acquired with a GE/VingMed Vivid 7 system (GE Healthcare, Milwaukee, WI) at 3.5 MHz and more than 100 frames/s. Eight different speeds (30-100 cycles/min of winding and unwinding) were studied at 5 degrees of rotation (10°, 20°, 30°, 40°, and 50°). Data were analyzed off-line for twist analysis with a new 2-dimensional speckle-tracking-based program (2-dimensional strain rate method [2DSR]) embedded in EchoPac software (GE Healthcare). Ten freshly harvested pig hearts were studied in this model. Results. The 2DSR program tracked the twist well (mean determination at 10° = 16.88° ± 1.81° [SD]; at 20° = 26.5° ± 1.05°; at 30° = 36.47° ± 1.31°; at 40° = 44.03° ± 1.39°; and at 50° = 54.1° ± 1.96°). Conclusions. The 2DSR program can be used to study twisting action of the heart.

Original languageEnglish (US)
Pages (from-to)1193-1198
Number of pages6
JournalJournal of Ultrasound in Medicine
Volume25
Issue number9
StatePublished - Sep 2006

Fingerprint

delineation
Validation Studies
twisting
strain rate
swine
stroke volume
abnormalities
wheels
Swine
contraction
baths
echoes
Delivery of Health Care
computer programs
cycles
Baths
Stroke Volume
Software
water
In Vitro Techniques

Keywords

  • Echocardiography
  • Heart function
  • Strain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

Cite this

Ashraf, M., Li, X. K., Young, M. T., Jensen, A. J., Pemberton, J., Hui, L., ... Sahn, D. (2006). Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method: An in vitro validation study. Journal of Ultrasound in Medicine, 25(9), 1193-1198.

Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method : An in vitro validation study. / Ashraf, Muhammad; Li, Xiao Kui; Young, Monica T.; Jensen, Amariek J.; Pemberton, James; Hui, Ling; Lysyansky, Peter; Friedman, Zvi; Park, Byung; Sahn, David.

In: Journal of Ultrasound in Medicine, Vol. 25, No. 9, 09.2006, p. 1193-1198.

Research output: Contribution to journalArticle

Ashraf, M, Li, XK, Young, MT, Jensen, AJ, Pemberton, J, Hui, L, Lysyansky, P, Friedman, Z, Park, B & Sahn, D 2006, 'Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method: An in vitro validation study', Journal of Ultrasound in Medicine, vol. 25, no. 9, pp. 1193-1198.
Ashraf, Muhammad ; Li, Xiao Kui ; Young, Monica T. ; Jensen, Amariek J. ; Pemberton, James ; Hui, Ling ; Lysyansky, Peter ; Friedman, Zvi ; Park, Byung ; Sahn, David. / Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method : An in vitro validation study. In: Journal of Ultrasound in Medicine. 2006 ; Vol. 25, No. 9. pp. 1193-1198.
@article{dc94719465514a95878e15c95c9e7c13,
title = "Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method: An in vitro validation study",
abstract = "Objective. Normal left ventricular contraction involves a twisting component that helps augment stroke volume, the unwinding of which also very usefully contributes to early diastolic filling. Abnormalities of cardiac twist have been related to abnormal cardiac function. We sought to quantify the twisting action using a new sonographically based angle-independent motion-detecting echo method. Methods. A twist model was developed with a variable-speed motor to rotate a wheel in water bath. A freshly harvested pig heart was mounted on it as a twist phantom. Short axis views were acquired with a GE/VingMed Vivid 7 system (GE Healthcare, Milwaukee, WI) at 3.5 MHz and more than 100 frames/s. Eight different speeds (30-100 cycles/min of winding and unwinding) were studied at 5 degrees of rotation (10°, 20°, 30°, 40°, and 50°). Data were analyzed off-line for twist analysis with a new 2-dimensional speckle-tracking-based program (2-dimensional strain rate method [2DSR]) embedded in EchoPac software (GE Healthcare). Ten freshly harvested pig hearts were studied in this model. Results. The 2DSR program tracked the twist well (mean determination at 10° = 16.88° ± 1.81° [SD]; at 20° = 26.5° ± 1.05°; at 30° = 36.47° ± 1.31°; at 40° = 44.03° ± 1.39°; and at 50° = 54.1° ± 1.96°). Conclusions. The 2DSR program can be used to study twisting action of the heart.",
keywords = "Echocardiography, Heart function, Strain",
author = "Muhammad Ashraf and Li, {Xiao Kui} and Young, {Monica T.} and Jensen, {Amariek J.} and James Pemberton and Ling Hui and Peter Lysyansky and Zvi Friedman and Byung Park and David Sahn",
year = "2006",
month = "9",
language = "English (US)",
volume = "25",
pages = "1193--1198",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "9",

}

TY - JOUR

T1 - Delineation of cardiac twist by a sonographically based 2-dimensional strain analysis method

T2 - An in vitro validation study

AU - Ashraf, Muhammad

AU - Li, Xiao Kui

AU - Young, Monica T.

AU - Jensen, Amariek J.

AU - Pemberton, James

AU - Hui, Ling

AU - Lysyansky, Peter

AU - Friedman, Zvi

AU - Park, Byung

AU - Sahn, David

PY - 2006/9

Y1 - 2006/9

N2 - Objective. Normal left ventricular contraction involves a twisting component that helps augment stroke volume, the unwinding of which also very usefully contributes to early diastolic filling. Abnormalities of cardiac twist have been related to abnormal cardiac function. We sought to quantify the twisting action using a new sonographically based angle-independent motion-detecting echo method. Methods. A twist model was developed with a variable-speed motor to rotate a wheel in water bath. A freshly harvested pig heart was mounted on it as a twist phantom. Short axis views were acquired with a GE/VingMed Vivid 7 system (GE Healthcare, Milwaukee, WI) at 3.5 MHz and more than 100 frames/s. Eight different speeds (30-100 cycles/min of winding and unwinding) were studied at 5 degrees of rotation (10°, 20°, 30°, 40°, and 50°). Data were analyzed off-line for twist analysis with a new 2-dimensional speckle-tracking-based program (2-dimensional strain rate method [2DSR]) embedded in EchoPac software (GE Healthcare). Ten freshly harvested pig hearts were studied in this model. Results. The 2DSR program tracked the twist well (mean determination at 10° = 16.88° ± 1.81° [SD]; at 20° = 26.5° ± 1.05°; at 30° = 36.47° ± 1.31°; at 40° = 44.03° ± 1.39°; and at 50° = 54.1° ± 1.96°). Conclusions. The 2DSR program can be used to study twisting action of the heart.

AB - Objective. Normal left ventricular contraction involves a twisting component that helps augment stroke volume, the unwinding of which also very usefully contributes to early diastolic filling. Abnormalities of cardiac twist have been related to abnormal cardiac function. We sought to quantify the twisting action using a new sonographically based angle-independent motion-detecting echo method. Methods. A twist model was developed with a variable-speed motor to rotate a wheel in water bath. A freshly harvested pig heart was mounted on it as a twist phantom. Short axis views were acquired with a GE/VingMed Vivid 7 system (GE Healthcare, Milwaukee, WI) at 3.5 MHz and more than 100 frames/s. Eight different speeds (30-100 cycles/min of winding and unwinding) were studied at 5 degrees of rotation (10°, 20°, 30°, 40°, and 50°). Data were analyzed off-line for twist analysis with a new 2-dimensional speckle-tracking-based program (2-dimensional strain rate method [2DSR]) embedded in EchoPac software (GE Healthcare). Ten freshly harvested pig hearts were studied in this model. Results. The 2DSR program tracked the twist well (mean determination at 10° = 16.88° ± 1.81° [SD]; at 20° = 26.5° ± 1.05°; at 30° = 36.47° ± 1.31°; at 40° = 44.03° ± 1.39°; and at 50° = 54.1° ± 1.96°). Conclusions. The 2DSR program can be used to study twisting action of the heart.

KW - Echocardiography

KW - Heart function

KW - Strain

UR - http://www.scopus.com/inward/record.url?scp=33748161127&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748161127&partnerID=8YFLogxK

M3 - Article

VL - 25

SP - 1193

EP - 1198

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

SN - 0278-4297

IS - 9

ER -