Daily Associations between Child and Parent Psychological Factors and Home Opioid Use in Youth with Sickle Cell Disease

Amanda L. Stone, Zaria Williams, Melissa McNaull, Anna C. Wilson, Cynthia W. Karlson

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Opioid analgesics are frequently used in the home setting to manage episodic pain in youth with sickle cell disease (SCD). Given the risk of adverse side effects, including constipation and sedation, understanding factors associated with at-home opioid use is important for maximizing pain relief while minimizing negative side effects. PURPOSE: The present study aimed to evaluate the relationship between individual psychological factors (pain catastrophizing and negative affect), caregiver psychological factors (catastrophizing about child's pain and caregiver negative affect), and home opioid use in youth with SCD. METHODS: Youth with SCD (n = 32) and a caregiver (n = 28) recruited during a routine outpatient hematology visit completed electronic 14 day diaries assessing pain, opioid use, and psychological factors. RESULTS: Approximately 28% of youth (n = 9) reported pain ≥50% of diary days and a third of youth (n = 11, 34%) used opioid analgesics at least one of the diary days. The number of days opioid analgesics were used ranged from 0 to 7 (50% of diary days). Results from generalized linear mixed models indicated greater child negative affect accounted for increased odds of opioid use on a given day when accounting for pain intensity. Greater caregiver catastrophizing about children's pain was also associated with increased odds of children's opioid use. CONCLUSIONS: Child and parent psychological factors relate to child opioid use at home for SCD-related pain. Future research is warranted in larger samples to identify targets for interventions to enhance pain management while reducing opioid-related risk and side effects.

Original languageEnglish (US)
Pages (from-to)61-66
Number of pages6
JournalAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine
Volume54
Issue number1
DOIs
StatePublished - Jan 1 2020

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Sickle Cell Anemia
Opioid Analgesics
Psychology
Pain
Catastrophization
Caregivers
Hematology
Constipation
Pain Management
Linear Models
Outpatients

Keywords

  • Hematology
  • Opioid
  • Pain
  • Pediatrics
  • Psychology
  • Sickle cell disease

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

Cite this

Daily Associations between Child and Parent Psychological Factors and Home Opioid Use in Youth with Sickle Cell Disease. / Stone, Amanda L.; Williams, Zaria; McNaull, Melissa; Wilson, Anna C.; Karlson, Cynthia W.

In: Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, Vol. 54, No. 1, 01.01.2020, p. 61-66.

Research output: Contribution to journalArticle

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