CX-4945, a selective inhibitor of casein kinase-2 (CK2), exhibits anti-tumor activity in hematologic malignancies including enhanced activity in chronic lymphocytic leukemia when combined with fludarabine and inhibitors of the B-cell receptor pathway

Research output: Contribution to journalArticle

32 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)2094-2096
Number of pages3
JournalLeukemia
Volume27
Issue number10
DOIs
StatePublished - Oct 2013

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Drug Synergism
Naphthyridines
Quinazolinones
Pyrazoles
Vidarabine
Casein Kinase II
Pyrimidines
Purines
B-Cell Antigen Receptors
Hematologic Neoplasms
B-Cell Chronic Lymphocytic Leukemia
Antineoplastic Agents
Signal Transduction
B-Lymphocytes
Immunoglobulin G
Neoplasms
5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid
fludarabine

ASJC Scopus subject areas

  • Hematology
  • Cancer Research
  • Anesthesiology and Pain Medicine

Cite this

@article{666eafa0954746c2b1d6d02317377a88,
title = "CX-4945, a selective inhibitor of casein kinase-2 (CK2), exhibits anti-tumor activity in hematologic malignancies including enhanced activity in chronic lymphocytic leukemia when combined with fludarabine and inhibitors of the B-cell receptor pathway",
author = "Prins, {R. C.} and Burke, {R. T.} and Jeffrey Tyner and Brian Druker and Marc Loriaux and Stephen Spurgeon",
year = "2013",
month = "10",
doi = "10.1038/leu.2013.228",
language = "English (US)",
volume = "27",
pages = "2094--2096",
journal = "Leukemia",
issn = "0887-6924",
publisher = "Nature Publishing Group",
number = "10",

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AU - Burke, R. T.

AU - Tyner, Jeffrey

AU - Druker, Brian

AU - Loriaux, Marc

AU - Spurgeon, Stephen

PY - 2013/10

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DO - 10.1038/leu.2013.228

M3 - Article

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VL - 27

SP - 2094

EP - 2096

JO - Leukemia

JF - Leukemia

SN - 0887-6924

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