Cutaneous manifestations of internal malignancies in a tertiary health care hospital of a developing country

Alex Ortega Loayza, Willy Ramos, Ericson L. Gutierrez, Patricia Chavez De Paz, Lucia Bobbio, Carlos Galarza

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In a public hospital in Lima, Peru, 24 patients with 16 types of paraneoplastic dermatoses were identified by data collection. The most frequent dermatosis was dermatomyositis (four patients). The other dermatoses were malignant acanthosis nigricans, palmoplantar keratoderma, bullous dermatoses, lymphomatoid papulosis, edematous scarring vasculitic panniculitis, Norwegian scabies, primary systemic amyloidosis, necrolytic migratory erythema, infective dermatitis, pancreatic panniculitis, generalized pruritus, Lesser-Trelat syndrome, and acquired ichthyosis. Most of these paraneoplastic dermatoses were diagnosed before (45.8%) or at the time of (38.5%) the diagnosis of the underlying malignancy. The most frequent underlying malignancies were lymphoma, adenocarcinomas of the upper digestive tract, and malignant neoplasms of the pancreas. The average age of the patients was 47.0 ± 16.9 years and the length of the disease since diagnosis was 13.7 months. The mortality rate was 75%. Paraneoplastic dermatoses are rare dermatologic entities that are difficult to diagnose. Surveillance is also hampered when patients do not have easy access to health care centers due to financial and geographical issues. However, when identified, they might facilitate the early diagnosis of an associated tumor and contribute to increase the surveillance of patients.

Original languageEnglish (US)
Pages (from-to)736-742
Number of pages7
JournalAnais Brasileiros de Dermatologia
Volume85
Issue number5
StatePublished - Sep 1 2010
Externally publishedYes

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Skin Manifestations
Tertiary Healthcare
Skin Diseases
Developing Countries
Delivery of Health Care
Panniculitis
Neoplasms
Necrolytic Migratory Erythema
Lymphomatoid Papulosis
Palmoplantar Keratoderma
Vesiculobullous Skin Diseases
Acanthosis Nigricans
Scabies
Peru
Health Services Accessibility
Dermatomyositis
Public Hospitals
Dermatitis
Pruritus
Pancreatic Neoplasms

Keywords

  • Dermatomyositis
  • Lymphoma
  • Paraneoplastic syndromes

ASJC Scopus subject areas

  • Dermatology

Cite this

Cutaneous manifestations of internal malignancies in a tertiary health care hospital of a developing country. / Ortega Loayza, Alex; Ramos, Willy; Gutierrez, Ericson L.; De Paz, Patricia Chavez; Bobbio, Lucia; Galarza, Carlos.

In: Anais Brasileiros de Dermatologia, Vol. 85, No. 5, 01.09.2010, p. 736-742.

Research output: Contribution to journalArticle

Ortega Loayza, Alex ; Ramos, Willy ; Gutierrez, Ericson L. ; De Paz, Patricia Chavez ; Bobbio, Lucia ; Galarza, Carlos. / Cutaneous manifestations of internal malignancies in a tertiary health care hospital of a developing country. In: Anais Brasileiros de Dermatologia. 2010 ; Vol. 85, No. 5. pp. 736-742.
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