Controversies in preterm brain injury

Anna A. Penn; Pierre Gressens; Bobbi Fleiss; Stephen Back; Vittorio Gallo

doi:10.1016/j.nbd.2015.10.012

Controversies in preterm brain injury

Anna A. Penn, Pierre Gressens, Bobbi Fleiss, Stephen Back, Vittorio Gallo

Pediatrics

Research output: Contribution to journal › Review article

32 Scopus citations

Abstract

In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

Original language	English (US)
Pages (from-to)	90-101
Number of pages	12
Journal	Neurobiology of Disease
Volume	92
Issue number	Part A
DOIs	https://doi.org/10.1016/j.nbd.2015.10.012
State	Published - 2016

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Keywords

Brain development
Neuroimaging
Preterm brain injury
White matter injury

ASJC Scopus subject areas

Neurology

Cite this

Penn, A. A., Gressens, P., Fleiss, B., Back, S., & Gallo, V. (2016). Controversies in preterm brain injury. Neurobiology of Disease, 92(Part A), 90-101. https://doi.org/10.1016/j.nbd.2015.10.012

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Access to Document

10.1016/j.nbd.2015.10.012