Abstract
In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.
Original language | English (US) |
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Pages (from-to) | 90-101 |
Number of pages | 12 |
Journal | Neurobiology of Disease |
Volume | 92 |
Issue number | Part A |
DOIs | |
State | Published - 2016 |
Keywords
- Brain development
- Neuroimaging
- Preterm brain injury
- White matter injury
ASJC Scopus subject areas
- Neurology