Abstract
In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 90-101 |
| Number of pages | 12 |
| Journal | Neurobiology of Disease |
| Volume | 92 |
| Issue number | Part A |
| DOIs | |
| State | Published - 2016 |
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Keywords
- Brain development
- Neuroimaging
- Preterm brain injury
- White matter injury
ASJC Scopus subject areas
- Neurology
Cite this
Controversies in preterm brain injury. / Penn, Anna A.; Gressens, Pierre; Fleiss, Bobbi; Back, Stephen; Gallo, Vittorio.
In: Neurobiology of Disease, Vol. 92, No. Part A, 2016, p. 90-101.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Controversies in preterm brain injury
AU - Penn, Anna A.
AU - Gressens, Pierre
AU - Fleiss, Bobbi
AU - Back, Stephen
AU - Gallo, Vittorio
PY - 2016
Y1 - 2016
N2 - In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.
AB - In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.
KW - Brain development
KW - Neuroimaging
KW - Preterm brain injury
KW - White matter injury
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UR - http://www.scopus.com/inward/citedby.url?scp=84979072415&partnerID=8YFLogxK
U2 - 10.1016/j.nbd.2015.10.012
DO - 10.1016/j.nbd.2015.10.012
M3 - Review article
C2 - 26477300
AN - SCOPUS:84979072415
VL - 92
SP - 90
EP - 101
JO - Neurobiology of Disease
JF - Neurobiology of Disease
SN - 0969-9961
IS - Part A
ER -