Consistent occurrence of a 19p+ marker chromosome and loss of 1 Ip material in ovarian seropapillary cystadenocarcinomas

Tanja Pejovic, S. Heim, N. Mandahl, B. Elmfors, U. M. Floderus, S. F urgyik, G. Helm, H. Willen, F. Mitelman

Research output: Contribution to journalArticle

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Abstract

Cytogenetic analysis of short-term cultures from 11 moderately to poorly differentiated ovarian seropapillary cystadenocarcinomas revealed clonal chromosomal abnormalities in nine tumors. Two bands were involved in structural rearrangements in more than half of the tumors. The band most frequently affected was 19p13; rearrangements giving rise to a 19p+ marker chromosome were found in seven tumors, and in four of them the 19p+ markers appeared to be identical. Structural rearrangements resulting in loss of 11p13-11pter material were found in six tumors.

Original languageEnglish (US)
Pages (from-to)167-171
Number of pages5
JournalGenes Chromosomes and Cancer
Volume1
Issue number2
StatePublished - 1989
Externally publishedYes

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Cystadenocarcinoma
Chromosomes, Human, Pair 1
Neoplasms
Cytogenetic Analysis
Genetic Markers
Chromosome Aberrations

ASJC Scopus subject areas

  • Cancer Research
  • Genetics

Cite this

Pejovic, T., Heim, S., Mandahl, N., Elmfors, B., Floderus, U. M., F urgyik, S., ... Mitelman, F. (1989). Consistent occurrence of a 19p+ marker chromosome and loss of 1 Ip material in ovarian seropapillary cystadenocarcinomas. Genes Chromosomes and Cancer, 1(2), 167-171.

Consistent occurrence of a 19p+ marker chromosome and loss of 1 Ip material in ovarian seropapillary cystadenocarcinomas. / Pejovic, Tanja; Heim, S.; Mandahl, N.; Elmfors, B.; Floderus, U. M.; F urgyik, S.; Helm, G.; Willen, H.; Mitelman, F.

In: Genes Chromosomes and Cancer, Vol. 1, No. 2, 1989, p. 167-171.

Research output: Contribution to journalArticle

Pejovic, T, Heim, S, Mandahl, N, Elmfors, B, Floderus, UM, F urgyik, S, Helm, G, Willen, H & Mitelman, F 1989, 'Consistent occurrence of a 19p+ marker chromosome and loss of 1 Ip material in ovarian seropapillary cystadenocarcinomas', Genes Chromosomes and Cancer, vol. 1, no. 2, pp. 167-171.
Pejovic, Tanja ; Heim, S. ; Mandahl, N. ; Elmfors, B. ; Floderus, U. M. ; F urgyik, S. ; Helm, G. ; Willen, H. ; Mitelman, F. / Consistent occurrence of a 19p+ marker chromosome and loss of 1 Ip material in ovarian seropapillary cystadenocarcinomas. In: Genes Chromosomes and Cancer. 1989 ; Vol. 1, No. 2. pp. 167-171.
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