Consistent occurrence of a 19p+ marker chromosome and loss of 11p material in ovarian seropapillary cystadenocarcinomas

Tanja Pejovic, Sverre Heim, Nils Mandahl, Bengt Elmfors, Ulla‐Maria ‐M Flodérus, Stefan Furgyik, Göran Helm, Helena Willén, Felix Mitelman

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Abstract

Cytogenetic analysis of short‐term cultures from 11 moderately to poorly differentiated ovarian seropapillary cystadenocarcinomas revealed clonal chromosomal abnormalities in nine tumors. Two bands were involved in structural rearrangements in more than half of the tumors. The band most frequently affected was 19p13; rearrangements giving rise to a 19p+ marker chromosome were found in seven tumors, and in four of them the 19p+ markers appeared to be identical. Structural rearrangements resulting in loss of 11p13‐11pter material were found in six tumors.

Original languageEnglish (US)
Pages (from-to)167-171
Number of pages5
JournalGenes, Chromosomes and Cancer
Volume1
Issue number2
DOIs
StatePublished - Nov 1989

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ASJC Scopus subject areas

  • Genetics
  • Cancer Research

Cite this

Pejovic, T., Heim, S., Mandahl, N., Elmfors, B., Flodérus, UM. M., Furgyik, S., Helm, G., Willén, H., & Mitelman, F. (1989). Consistent occurrence of a 19p+ marker chromosome and loss of 11p material in ovarian seropapillary cystadenocarcinomas. Genes, Chromosomes and Cancer, 1(2), 167-171. https://doi.org/10.1002/gcc.2870010210