Congenital sarcoma in the terminal ileum histologically resembling clear cell sarcoma of the kidney: A case report with an immunohistochemical study

Yoshiko Kataoka, Hiroyuki Shimada, Tohru Sugimoto, Hiroshi Mine, Yoichi Hachitanda, Yasuo Doi, Tadashi Sawada, Douglas A. Weeks

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

We report a case of a newborn female with a rare tumor, a congenital sarcoma, presenting as an abdominal mass. Laparotomy demonstrated the tumor arising from the wall of the terminal ileum. Histologically, the tumor tissue was indistinguishable from clear cell sarcoma of the kidney and was composed of proliferating cells with poorly stained cytoplasm divided into nests or cords by arborizing vasculature. Immunohistochemical staining revealed that the neoplastic cells had a phenotype similar to metanephric blastemal cells of fetal kidney, ie, positive for vimentin and CD24 but negative for cytokeratin and CD9. The results suggest that this congenital tumor may originate from primitive mesenchymal cells phenotypically related to cells present in the fetal kidney.

Original languageEnglish (US)
Pages (from-to)1026-1030
Number of pages5
JournalHuman Pathology
Volume24
Issue number9
DOIs
StatePublished - Sep 1993

Keywords

  • CD10
  • CD24
  • CD9
  • clear cell sarcoma of the kidney
  • congenital sarcoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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