Computed tomography and magnetic resonance imaging of adult renal cell carcinoma associated with Xp11.2 translocation

Trien T. Dang, Etay Ziv, Stefanie Weinstein, Maxwell V. Meng, Zhen Wang, Fergus Coakley

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objective: This study aimed to report the computed tomography (CT) and magnetic resonance imaging (MRI) findings of renal cell carcinoma associated with Xp11.2 translocation in adults. Methods: We retrospectively identified 9 adults with renal cell carcinoma associated with Xp11.2 translocation who underwent baseline cross-sectional imaging with CT (n = 9) or MRI (n = 3). All available clinical, imaging, and histopathological records were reviewed. Results: Mean patient age was 24 years (range, 18-45 years). Eight of 9 cancers demonstrated imaging findings of hemorrhage or necrosis (n = 3), advanced stage disease (n = 2), or both (n = 3) at CT or MRI. Conclusions: The possibility of renal cell carcinoma associated with Xp11.2 translocation should be considered for a renal mass seen in a patient 45 years or younger, which demonstrates hemorrhage or necrosis or advanced stage disease at CT or MRI.

Original languageEnglish (US)
Pages (from-to)669-674
Number of pages6
JournalJournal of Computer Assisted Tomography
Volume36
Issue number6
DOIs
StatePublished - Nov 2012

Fingerprint

Renal Cell Carcinoma
Tomography
Magnetic Resonance Imaging
Necrosis
Hemorrhage
Kidney
Neoplasms

Keywords

  • CT
  • MRI
  • Renal cell carcinoma
  • TFE3 gene fusion carcinoma
  • Xp11.2 translocation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Computed tomography and magnetic resonance imaging of adult renal cell carcinoma associated with Xp11.2 translocation. / Dang, Trien T.; Ziv, Etay; Weinstein, Stefanie; Meng, Maxwell V.; Wang, Zhen; Coakley, Fergus.

In: Journal of Computer Assisted Tomography, Vol. 36, No. 6, 11.2012, p. 669-674.

Research output: Contribution to journalArticle

Dang, Trien T. ; Ziv, Etay ; Weinstein, Stefanie ; Meng, Maxwell V. ; Wang, Zhen ; Coakley, Fergus. / Computed tomography and magnetic resonance imaging of adult renal cell carcinoma associated with Xp11.2 translocation. In: Journal of Computer Assisted Tomography. 2012 ; Vol. 36, No. 6. pp. 669-674.
@article{a30b0dbf07f544048666e7eb913cf121,
title = "Computed tomography and magnetic resonance imaging of adult renal cell carcinoma associated with Xp11.2 translocation",
abstract = "Objective: This study aimed to report the computed tomography (CT) and magnetic resonance imaging (MRI) findings of renal cell carcinoma associated with Xp11.2 translocation in adults. Methods: We retrospectively identified 9 adults with renal cell carcinoma associated with Xp11.2 translocation who underwent baseline cross-sectional imaging with CT (n = 9) or MRI (n = 3). All available clinical, imaging, and histopathological records were reviewed. Results: Mean patient age was 24 years (range, 18-45 years). Eight of 9 cancers demonstrated imaging findings of hemorrhage or necrosis (n = 3), advanced stage disease (n = 2), or both (n = 3) at CT or MRI. Conclusions: The possibility of renal cell carcinoma associated with Xp11.2 translocation should be considered for a renal mass seen in a patient 45 years or younger, which demonstrates hemorrhage or necrosis or advanced stage disease at CT or MRI.",
keywords = "CT, MRI, Renal cell carcinoma, TFE3 gene fusion carcinoma, Xp11.2 translocation",
author = "Dang, {Trien T.} and Etay Ziv and Stefanie Weinstein and Meng, {Maxwell V.} and Zhen Wang and Fergus Coakley",
year = "2012",
month = "11",
doi = "10.1097/RCT.0b013e3182680182",
language = "English (US)",
volume = "36",
pages = "669--674",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Computed tomography and magnetic resonance imaging of adult renal cell carcinoma associated with Xp11.2 translocation

AU - Dang, Trien T.

AU - Ziv, Etay

AU - Weinstein, Stefanie

AU - Meng, Maxwell V.

AU - Wang, Zhen

AU - Coakley, Fergus

PY - 2012/11

Y1 - 2012/11

N2 - Objective: This study aimed to report the computed tomography (CT) and magnetic resonance imaging (MRI) findings of renal cell carcinoma associated with Xp11.2 translocation in adults. Methods: We retrospectively identified 9 adults with renal cell carcinoma associated with Xp11.2 translocation who underwent baseline cross-sectional imaging with CT (n = 9) or MRI (n = 3). All available clinical, imaging, and histopathological records were reviewed. Results: Mean patient age was 24 years (range, 18-45 years). Eight of 9 cancers demonstrated imaging findings of hemorrhage or necrosis (n = 3), advanced stage disease (n = 2), or both (n = 3) at CT or MRI. Conclusions: The possibility of renal cell carcinoma associated with Xp11.2 translocation should be considered for a renal mass seen in a patient 45 years or younger, which demonstrates hemorrhage or necrosis or advanced stage disease at CT or MRI.

AB - Objective: This study aimed to report the computed tomography (CT) and magnetic resonance imaging (MRI) findings of renal cell carcinoma associated with Xp11.2 translocation in adults. Methods: We retrospectively identified 9 adults with renal cell carcinoma associated with Xp11.2 translocation who underwent baseline cross-sectional imaging with CT (n = 9) or MRI (n = 3). All available clinical, imaging, and histopathological records were reviewed. Results: Mean patient age was 24 years (range, 18-45 years). Eight of 9 cancers demonstrated imaging findings of hemorrhage or necrosis (n = 3), advanced stage disease (n = 2), or both (n = 3) at CT or MRI. Conclusions: The possibility of renal cell carcinoma associated with Xp11.2 translocation should be considered for a renal mass seen in a patient 45 years or younger, which demonstrates hemorrhage or necrosis or advanced stage disease at CT or MRI.

KW - CT

KW - MRI

KW - Renal cell carcinoma

KW - TFE3 gene fusion carcinoma

KW - Xp11.2 translocation

UR - http://www.scopus.com/inward/record.url?scp=84870877893&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870877893&partnerID=8YFLogxK

U2 - 10.1097/RCT.0b013e3182680182

DO - 10.1097/RCT.0b013e3182680182

M3 - Article

VL - 36

SP - 669

EP - 674

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

IS - 6

ER -