Comparison of spirometry criteria for the diagnosis of COPD: Results from the BOLD study

W. M. Vollmer, P. Gíslason, P. Burney, P. L. Enrigh, A. Gulsvik, A. Kocabas, A (Sonia) Buist

Research output: Contribution to journalArticle

173 Citations (Scopus)

Abstract

Published guidelines recommend spirometry to accurately diagnose chronic obstructive pulmonary disease (COPD). However, even spirometry-based COPD prevalence estimates can vary widely. We compared properties of several spirometry-based COPD definitions using data from the international Burden of Obstructive Lung Disease (BOLD)study. 14 sites recruited population-based samples of adults aged ≥40 yrs. Procedures included standardised questionnaires and post-bronchodilator spirometry. 10,001 individuals provided usable data. Use of the lower limit of normal (LLN) forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio reduced the age-related increases in COPD prevalence that are seen among healthy never-smokers when using the fixed ratio criterion (FEV1/FVC 1 either 1/FEV6 ratio in place of the FEV 1/FVC yielded similar prevalence estimates. Use of the FEV 1/FVC1/FVC 1/FEV6 as a practical substitute for the FEV 1/FVC. Copyright

Original languageEnglish (US)
Pages (from-to)588-597
Number of pages10
JournalEuropean Respiratory Journal
Volume34
Issue number3
DOIs
StatePublished - Sep 2009

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Obstructive Lung Diseases
Spirometry
Vital Capacity
Chronic Obstructive Pulmonary Disease
Forced Expiratory Volume
Bronchodilator Agents
Guidelines
Population

Keywords

  • Adult
  • Chronic obstructive pulmonary disease
  • Epidemiology

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Comparison of spirometry criteria for the diagnosis of COPD : Results from the BOLD study. / Vollmer, W. M.; Gíslason, P.; Burney, P.; Enrigh, P. L.; Gulsvik, A.; Kocabas, A.; Buist, A (Sonia).

In: European Respiratory Journal, Vol. 34, No. 3, 09.2009, p. 588-597.

Research output: Contribution to journalArticle

Vollmer, WM, Gíslason, P, Burney, P, Enrigh, PL, Gulsvik, A, Kocabas, A & Buist, AS 2009, 'Comparison of spirometry criteria for the diagnosis of COPD: Results from the BOLD study', European Respiratory Journal, vol. 34, no. 3, pp. 588-597. https://doi.org/10.1183/09031936.00164608
Vollmer, W. M. ; Gíslason, P. ; Burney, P. ; Enrigh, P. L. ; Gulsvik, A. ; Kocabas, A. ; Buist, A (Sonia). / Comparison of spirometry criteria for the diagnosis of COPD : Results from the BOLD study. In: European Respiratory Journal. 2009 ; Vol. 34, No. 3. pp. 588-597.
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