Comparison of digital fundus photographic and echographic measurements for maximal linear dimension from eyes with choroidal melanoma

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

PURPOSE: Accurate assessment of tumor size is crucial in the treatment of choroidal melanoma. Digital fundus photographic systems can create a montage that clearly documents the tumor margins. These images can be used to measure tumor maximal linear dimension (MLD). This study evaluates the potential value of a digital imaging system compared with echography in measuring the MLD of choroidal melanoma. METHODS: Echographic measurements were performed in a standardized fashion following Collaborative Ocular Melanoma Study (COMS) methods. For photographic measurements, the tumor margin was outlined with an electronic pen and the MLD were calculated by software (ANKA-ProView, Topcon Medical Systems, Paramus, NJ). RESULTS: The mean MLD before I-125 brachytherapy was 9.32 mm by echography and 10.57 mm by digital photography analysis. This difference was statistically significant (P <0.001). The 2 measurements of MLD agreed within 1.1 mm for 11 eyes (52%) and 2.2 mm for 20 eyes (95%). Digital photographic analysis estimated a larger MLD in 19 of the 21 eyes compared with echography. CONCLUSION: This discrepancy likely results from the photographic measurement more accurately assessing the flat portion of the tumor. Digital photographic analysis may allow clinicians to determine the MLD of tumors more accurately than echography. This could increase the rate of successful treatment with brachytherapy.

Original languageEnglish (US)
Pages (from-to)1321-1327
Number of pages7
JournalRetina
Volume29
Issue number9
DOIs
StatePublished - Oct 2009

Fingerprint

Melanoma
Ultrasonography
Neoplasms
Brachytherapy
Photography
Software
Therapeutics

Keywords

  • Choroidal melanoma
  • Digital fundus photographic measurement
  • Echographic measurement
  • Tumor maximal linear dimension

ASJC Scopus subject areas

  • Ophthalmology

Cite this

@article{1f16cb42ed6641a792f0b454911316ab,
title = "Comparison of digital fundus photographic and echographic measurements for maximal linear dimension from eyes with choroidal melanoma",
abstract = "PURPOSE: Accurate assessment of tumor size is crucial in the treatment of choroidal melanoma. Digital fundus photographic systems can create a montage that clearly documents the tumor margins. These images can be used to measure tumor maximal linear dimension (MLD). This study evaluates the potential value of a digital imaging system compared with echography in measuring the MLD of choroidal melanoma. METHODS: Echographic measurements were performed in a standardized fashion following Collaborative Ocular Melanoma Study (COMS) methods. For photographic measurements, the tumor margin was outlined with an electronic pen and the MLD were calculated by software (ANKA-ProView, Topcon Medical Systems, Paramus, NJ). RESULTS: The mean MLD before I-125 brachytherapy was 9.32 mm by echography and 10.57 mm by digital photography analysis. This difference was statistically significant (P <0.001). The 2 measurements of MLD agreed within 1.1 mm for 11 eyes (52{\%}) and 2.2 mm for 20 eyes (95{\%}). Digital photographic analysis estimated a larger MLD in 19 of the 21 eyes compared with echography. CONCLUSION: This discrepancy likely results from the photographic measurement more accurately assessing the flat portion of the tumor. Digital photographic analysis may allow clinicians to determine the MLD of tumors more accurately than echography. This could increase the rate of successful treatment with brachytherapy.",
keywords = "Choroidal melanoma, Digital fundus photographic measurement, Echographic measurement, Tumor maximal linear dimension",
author = "Yunyoung Kim and Thomas Hwang and Dongseok Choi and David Wilson",
year = "2009",
month = "10",
doi = "10.1097/IAE.0b013e3181aa40a2",
language = "English (US)",
volume = "29",
pages = "1321--1327",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Comparison of digital fundus photographic and echographic measurements for maximal linear dimension from eyes with choroidal melanoma

AU - Kim, Yunyoung

AU - Hwang, Thomas

AU - Choi, Dongseok

AU - Wilson, David

PY - 2009/10

Y1 - 2009/10

N2 - PURPOSE: Accurate assessment of tumor size is crucial in the treatment of choroidal melanoma. Digital fundus photographic systems can create a montage that clearly documents the tumor margins. These images can be used to measure tumor maximal linear dimension (MLD). This study evaluates the potential value of a digital imaging system compared with echography in measuring the MLD of choroidal melanoma. METHODS: Echographic measurements were performed in a standardized fashion following Collaborative Ocular Melanoma Study (COMS) methods. For photographic measurements, the tumor margin was outlined with an electronic pen and the MLD were calculated by software (ANKA-ProView, Topcon Medical Systems, Paramus, NJ). RESULTS: The mean MLD before I-125 brachytherapy was 9.32 mm by echography and 10.57 mm by digital photography analysis. This difference was statistically significant (P <0.001). The 2 measurements of MLD agreed within 1.1 mm for 11 eyes (52%) and 2.2 mm for 20 eyes (95%). Digital photographic analysis estimated a larger MLD in 19 of the 21 eyes compared with echography. CONCLUSION: This discrepancy likely results from the photographic measurement more accurately assessing the flat portion of the tumor. Digital photographic analysis may allow clinicians to determine the MLD of tumors more accurately than echography. This could increase the rate of successful treatment with brachytherapy.

AB - PURPOSE: Accurate assessment of tumor size is crucial in the treatment of choroidal melanoma. Digital fundus photographic systems can create a montage that clearly documents the tumor margins. These images can be used to measure tumor maximal linear dimension (MLD). This study evaluates the potential value of a digital imaging system compared with echography in measuring the MLD of choroidal melanoma. METHODS: Echographic measurements were performed in a standardized fashion following Collaborative Ocular Melanoma Study (COMS) methods. For photographic measurements, the tumor margin was outlined with an electronic pen and the MLD were calculated by software (ANKA-ProView, Topcon Medical Systems, Paramus, NJ). RESULTS: The mean MLD before I-125 brachytherapy was 9.32 mm by echography and 10.57 mm by digital photography analysis. This difference was statistically significant (P <0.001). The 2 measurements of MLD agreed within 1.1 mm for 11 eyes (52%) and 2.2 mm for 20 eyes (95%). Digital photographic analysis estimated a larger MLD in 19 of the 21 eyes compared with echography. CONCLUSION: This discrepancy likely results from the photographic measurement more accurately assessing the flat portion of the tumor. Digital photographic analysis may allow clinicians to determine the MLD of tumors more accurately than echography. This could increase the rate of successful treatment with brachytherapy.

KW - Choroidal melanoma

KW - Digital fundus photographic measurement

KW - Echographic measurement

KW - Tumor maximal linear dimension

UR - http://www.scopus.com/inward/record.url?scp=70350163315&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350163315&partnerID=8YFLogxK

U2 - 10.1097/IAE.0b013e3181aa40a2

DO - 10.1097/IAE.0b013e3181aa40a2

M3 - Article

C2 - 19672217

AN - SCOPUS:70350163315

VL - 29

SP - 1321

EP - 1327

JO - Retina

JF - Retina

SN - 0275-004X

IS - 9

ER -