Comparative nephrotoxicities of high-dose netilmicin and tobramycin in rats

R. A. Parker, D. N. Gilbert, D. C. Houghton, G. A. Porter, W. M. Bennett

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The nephrotoxic potentials of netilmicin and tobramycin given in doses of 180 mg/kg per day for up to 14 days in rats. At this dosage, tobramycin produced mortality and significant changes in renal structure and function; netilmicin evoked minimal nephrotoxicity.

Original languageEnglish (US)
Pages (from-to)346-348
Number of pages3
JournalUnknown Journal
Volume18
Issue number2
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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