Clear-cell follicular adenoma of ectopic thyroid in the submandibular region

Dilip Giri; S. Humayun Gultekin; Robert F. Ward; James R. Hurley; Syed A. Hoda

doi:10.1007/BF02739695

Clear-cell follicular adenoma of ectopic thyroid in the submandibular region

Dilip Giri, S. Humayun Gultekin, Robert F. Ward, James R. Hurley, Syed A. Hoda

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A case of clear-cell follicular adenoma arising in ectopic thyroid tissue is reported. The 2.0-cm tumor arose in the submandibular region in a 29-yr-old female. The diagnosis was established on the basis of light microscopic morphology, a positive thyroglobulin immunohistology, and the presence of normal thyroid tissue surrounding the mass. Preoperative computed tomography (CT) scan and postoperative ultrasound studies revealed a normal orthotopic thyroid gland. No additional tumors have since been detected. The patient is free of recurrent or metastatic disease 54 mo following excision of the mass. Only eight previously published reports have described ectopic thyroid tissue in the submandibular region, all but one of which lacked an orthotopic thyroid gland. In this article, we describe the pathological features of our case and review the existing literature on the subject.

Original language	English (US)
Pages (from-to)	347-351
Number of pages	5
Journal	Endocrine Pathology
Volume	9
Issue number	4
DOIs	https://doi.org/10.1007/BF02739695
State	Published - 1998
Externally published	Yes

Keywords

Ectopic thyroid
Follicular adenoma
Submandibular region

ASJC Scopus subject areas

Pathology and Forensic Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1007/BF02739695

Cite this

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title = "Clear-cell follicular adenoma of ectopic thyroid in the submandibular region",

abstract = "A case of clear-cell follicular adenoma arising in ectopic thyroid tissue is reported. The 2.0-cm tumor arose in the submandibular region in a 29-yr-old female. The diagnosis was established on the basis of light microscopic morphology, a positive thyroglobulin immunohistology, and the presence of normal thyroid tissue surrounding the mass. Preoperative computed tomography (CT) scan and postoperative ultrasound studies revealed a normal orthotopic thyroid gland. No additional tumors have since been detected. The patient is free of recurrent or metastatic disease 54 mo following excision of the mass. Only eight previously published reports have described ectopic thyroid tissue in the submandibular region, all but one of which lacked an orthotopic thyroid gland. In this article, we describe the pathological features of our case and review the existing literature on the subject.",

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T1 - Clear-cell follicular adenoma of ectopic thyroid in the submandibular region

AU - Giri, Dilip

AU - Gultekin, S. Humayun

AU - Ward, Robert F.

AU - Hurley, James R.

AU - Hoda, Syed A.

PY - 1998

Y1 - 1998

N2 - A case of clear-cell follicular adenoma arising in ectopic thyroid tissue is reported. The 2.0-cm tumor arose in the submandibular region in a 29-yr-old female. The diagnosis was established on the basis of light microscopic morphology, a positive thyroglobulin immunohistology, and the presence of normal thyroid tissue surrounding the mass. Preoperative computed tomography (CT) scan and postoperative ultrasound studies revealed a normal orthotopic thyroid gland. No additional tumors have since been detected. The patient is free of recurrent or metastatic disease 54 mo following excision of the mass. Only eight previously published reports have described ectopic thyroid tissue in the submandibular region, all but one of which lacked an orthotopic thyroid gland. In this article, we describe the pathological features of our case and review the existing literature on the subject.

AB - A case of clear-cell follicular adenoma arising in ectopic thyroid tissue is reported. The 2.0-cm tumor arose in the submandibular region in a 29-yr-old female. The diagnosis was established on the basis of light microscopic morphology, a positive thyroglobulin immunohistology, and the presence of normal thyroid tissue surrounding the mass. Preoperative computed tomography (CT) scan and postoperative ultrasound studies revealed a normal orthotopic thyroid gland. No additional tumors have since been detected. The patient is free of recurrent or metastatic disease 54 mo following excision of the mass. Only eight previously published reports have described ectopic thyroid tissue in the submandibular region, all but one of which lacked an orthotopic thyroid gland. In this article, we describe the pathological features of our case and review the existing literature on the subject.

KW - Ectopic thyroid

KW - Follicular adenoma

KW - Submandibular region

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Clear-cell follicular adenoma of ectopic thyroid in the submandibular region

Abstract

Keywords

ASJC Scopus subject areas

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