Chronic infiltrative lung disease

Comparison of diagnostic accuracies of radiography and low- and conventional-dose thin-section CT

Kyung Soo Lee, Steven Primack, Catherine A. Staples, John R. Mayo, John E. Aldrich, Nestor L. Müller

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Abstract

PURPOSE: To compare the accuracy of low-dose thin-section computed tomography (CT), chest radiography, and conventional-dose thin-section CT in diagnosis of chronic infiltrative lung disease (CILD). MATERIALS AND METHODS: Chest radiographs and low-dose (80-mAs) and conventional-dose (340-mAs) thin- section (1.5-mm) CT scans from 50 patients with CILD and 10 healthy control subjects were randomized and analyzed retrospectively. For CT, three images were obtained: at the aortic arch, at the tracheal carina, and 1 cm above the right hemidiaphragm. Two independent observers listed three likely diagnoses and recorded the degree of confidence in their first choice. RESULTS: A correct first-choice diagnosis was made more often with either CT technique than with radiography (P <.02). A high confidence level in the diagnosis was reached in 42% of radiographic, 61% of low-dose CT, and 63% of conventional- dose CT interpretations, which were correct in 92%, 90%, and 96% of the studies, respectively. CONCLUSION: The superior diagnostic accuracy of low- dose thin-section CT was achieved without an increase in effective radiation dose.

Original languageEnglish (US)
Pages (from-to)669-673
Number of pages5
JournalRadiology
Volume191
Issue number3
StatePublished - Jun 1994
Externally publishedYes

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Radiography
Lung Diseases
Tomography
Thorax
Thoracic Aorta
Healthy Volunteers
Radiation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Lee, K. S., Primack, S., Staples, C. A., Mayo, J. R., Aldrich, J. E., & Müller, N. L. (1994). Chronic infiltrative lung disease: Comparison of diagnostic accuracies of radiography and low- and conventional-dose thin-section CT. Radiology, 191(3), 669-673.

Chronic infiltrative lung disease : Comparison of diagnostic accuracies of radiography and low- and conventional-dose thin-section CT. / Lee, Kyung Soo; Primack, Steven; Staples, Catherine A.; Mayo, John R.; Aldrich, John E.; Müller, Nestor L.

In: Radiology, Vol. 191, No. 3, 06.1994, p. 669-673.

Research output: Contribution to journalArticle

Lee, Kyung Soo ; Primack, Steven ; Staples, Catherine A. ; Mayo, John R. ; Aldrich, John E. ; Müller, Nestor L. / Chronic infiltrative lung disease : Comparison of diagnostic accuracies of radiography and low- and conventional-dose thin-section CT. In: Radiology. 1994 ; Vol. 191, No. 3. pp. 669-673.
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abstract = "PURPOSE: To compare the accuracy of low-dose thin-section computed tomography (CT), chest radiography, and conventional-dose thin-section CT in diagnosis of chronic infiltrative lung disease (CILD). MATERIALS AND METHODS: Chest radiographs and low-dose (80-mAs) and conventional-dose (340-mAs) thin- section (1.5-mm) CT scans from 50 patients with CILD and 10 healthy control subjects were randomized and analyzed retrospectively. For CT, three images were obtained: at the aortic arch, at the tracheal carina, and 1 cm above the right hemidiaphragm. Two independent observers listed three likely diagnoses and recorded the degree of confidence in their first choice. RESULTS: A correct first-choice diagnosis was made more often with either CT technique than with radiography (P <.02). A high confidence level in the diagnosis was reached in 42{\%} of radiographic, 61{\%} of low-dose CT, and 63{\%} of conventional- dose CT interpretations, which were correct in 92{\%}, 90{\%}, and 96{\%} of the studies, respectively. CONCLUSION: The superior diagnostic accuracy of low- dose thin-section CT was achieved without an increase in effective radiation dose.",
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AU - Mayo, John R.

AU - Aldrich, John E.

AU - Müller, Nestor L.

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N2 - PURPOSE: To compare the accuracy of low-dose thin-section computed tomography (CT), chest radiography, and conventional-dose thin-section CT in diagnosis of chronic infiltrative lung disease (CILD). MATERIALS AND METHODS: Chest radiographs and low-dose (80-mAs) and conventional-dose (340-mAs) thin- section (1.5-mm) CT scans from 50 patients with CILD and 10 healthy control subjects were randomized and analyzed retrospectively. For CT, three images were obtained: at the aortic arch, at the tracheal carina, and 1 cm above the right hemidiaphragm. Two independent observers listed three likely diagnoses and recorded the degree of confidence in their first choice. RESULTS: A correct first-choice diagnosis was made more often with either CT technique than with radiography (P <.02). A high confidence level in the diagnosis was reached in 42% of radiographic, 61% of low-dose CT, and 63% of conventional- dose CT interpretations, which were correct in 92%, 90%, and 96% of the studies, respectively. CONCLUSION: The superior diagnostic accuracy of low- dose thin-section CT was achieved without an increase in effective radiation dose.

AB - PURPOSE: To compare the accuracy of low-dose thin-section computed tomography (CT), chest radiography, and conventional-dose thin-section CT in diagnosis of chronic infiltrative lung disease (CILD). MATERIALS AND METHODS: Chest radiographs and low-dose (80-mAs) and conventional-dose (340-mAs) thin- section (1.5-mm) CT scans from 50 patients with CILD and 10 healthy control subjects were randomized and analyzed retrospectively. For CT, three images were obtained: at the aortic arch, at the tracheal carina, and 1 cm above the right hemidiaphragm. Two independent observers listed three likely diagnoses and recorded the degree of confidence in their first choice. RESULTS: A correct first-choice diagnosis was made more often with either CT technique than with radiography (P <.02). A high confidence level in the diagnosis was reached in 42% of radiographic, 61% of low-dose CT, and 63% of conventional- dose CT interpretations, which were correct in 92%, 90%, and 96% of the studies, respectively. CONCLUSION: The superior diagnostic accuracy of low- dose thin-section CT was achieved without an increase in effective radiation dose.

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