Childhood gastroesophageal reflux symptoms in adult patients

J. Patrick Waring, Michael J. Feiler, John Hunter, C. Daniel Smith, Benjamin D. Gold

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Objectives: Gastroesophageal reflux (GER) and its esophageal (esophagitis, Barrett's esophagus) and extraesophageal (asthma, laryngeal disease) disease manifestations (GERD) are increasing common problems in children and adults. There are virtually no published longitudinal outcome studies that describe the natural history of childhood-onset GER throughout a person's lifetime. The aim of this study was to compare the frequency of recalled childhood reflux symptoms in adult patients currently with and without GER symptoms. Methods: Four hundred adult patients were classified as refluxers (225 patients; 57%), nonrefluxers (154 patients; 38%), and those who claimed to not know if they had reflux (21 patients; 5%; excluded from analysis). Subjects were given a questionnaire asking them to recall childhood symptoms attributed to GER. Of the 225 refluxers, 141 (63%) recalled at least one childhood symptom, compared with 54 of the 154 nonrefluxers (35%) (P <0.001). Conclusions: Adult refluxers were more likely to recall having developed GER symptoms at an earlier age, beginning at infancy and developing statistically significant GER compared with nonrefluxers after age 11. Adults suffering from GER were far more likely than nonrefluxers to recall having experienced GER symptoms during childhood. Well-designed, population-based epidemiologic studies are needed to more accurately assess the extent of GER in the overall population and the extent of its impact on health care in the United States.

Original languageEnglish (US)
Pages (from-to)334-338
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume35
Issue number3
DOIs
StatePublished - Sep 2002
Externally publishedYes

Fingerprint

gastroesophageal reflux
Gastroesophageal Reflux
childhood
signs and symptoms (animals and humans)
Laryngeal Diseases
esophageal diseases
asthma
infancy
Barrett Esophagus
Esophagitis
esophagus
natural history
health services
epidemiological studies
Natural History
Population
Longitudinal Studies
questionnaires
Epidemiologic Studies
Asthma

Keywords

  • Childhood
  • Gastroesophageal reflux disease
  • Symptoms

ASJC Scopus subject areas

  • Gastroenterology
  • Histology
  • Medicine (miscellaneous)
  • Food Science
  • Pediatrics, Perinatology, and Child Health

Cite this

Childhood gastroesophageal reflux symptoms in adult patients. / Waring, J. Patrick; Feiler, Michael J.; Hunter, John; Smith, C. Daniel; Gold, Benjamin D.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 35, No. 3, 09.2002, p. 334-338.

Research output: Contribution to journalArticle

Waring, J. Patrick ; Feiler, Michael J. ; Hunter, John ; Smith, C. Daniel ; Gold, Benjamin D. / Childhood gastroesophageal reflux symptoms in adult patients. In: Journal of Pediatric Gastroenterology and Nutrition. 2002 ; Vol. 35, No. 3. pp. 334-338.
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