Characteristics of women who refuse an offer of prenatal diagnosis: Data from the California maternal serum alpha fetoprotein blood test experience

Nancy Press, C. H. Browner

    Research output: Contribution to journalArticle

    67 Scopus citations

    Abstract

    This paper presents data from the California maternal serum alpha fetoprotein (MSAFP) program in order to explore the effect and interaction of various factors, especially ethnicity, abortion history and attitudes, religion, and religiosity on MSAFP test decision. The intent is to describe which women are more likely to reject MSAFP screening and also to understand the reasons for refusal and the meanings associated with it. We obtained data on sociodemographics and reproductive history from 595 obstetrical patient charts; we conducted semistructured interviews with an additional 158 pregnant women who were European-American, English-speaking Latina, or Spanish-speaking Latina. All of the women had been offered screening within the context of California's MSAFP Program. We found that women who had never terminated a pregnancy, Spanish-speaking Latinas, and women who scored high on a religiosity scale were significantly more likely to refuse testing. However, we found that all of those factors were strongly mediated by the effects of ethnicity and acculturation, producing different patterns of association in different groups of women.

    Original languageEnglish (US)
    Pages (from-to)433-445
    Number of pages13
    JournalAmerican Journal of Medical Genetics
    Volume78
    Issue number5
    DOIs
    StatePublished - Aug 6 1998

    Keywords

    • Abortion
    • Ethnicity
    • Maternal serum alpha fetoprotein
    • Prenatal diagnosis
    • Religiosity

    ASJC Scopus subject areas

    • Genetics
    • Genetics(clinical)

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