Changes in physical performance in older women according to presence and treatment of diabetes mellitus

Christine Lee, Ann V. Schwartz, Kristine Yaffe, Teresa A. Hillier, Erin S. Leblanc, Peggy M. Cawthon

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objectives To determine whether older women with diabetes mellitus have a greater longitudinal decline in physical performance than those without and whether any decline differs according to insulin sensitizer use. Design Prospective cohort study. Setting Baltimore, Maryland; Minneapolis, Minnesota; Portland, Oregon; and the Monongahela, Pennsylvania. Participants Community-dwelling women (mean age 78.5 ± 3.6) enrolled in the Study of Osteoporotic Fractures in 1997-98 and restudied 4.9 ± 0.6 years later (N = 2,864). Measurements Women were categorized as having no diabetes mellitus (n = 2,680) or having diabetes mellitus (n = 184). A prescription medication inventory was used to determine use of insulin sensitizers (metformin and thiazolidinedione). The outcomes were longitudinal changes in physical performance measures, including grip strength, usual walk speed, and rapid walk speed. Results Estimates from fully adjusted models showed that women with diabetes mellitus had greater declines in usual walk speed (-0.16 m/s, 95% confidence interval (CI) = -0.19 to -0.14) and rapid walk speed (-0.21 m/s, 95% CI = -0.24 to -0.17) than those without (usual walk speed -0.11 m/s, 95% CI = -0.12 to -0.11, P

Original languageEnglish (US)
Pages (from-to)1872-1878
Number of pages7
JournalJournal of the American Geriatrics Society
Volume61
Issue number11
DOIs
StatePublished - Nov 2013

Fingerprint

Diabetes Mellitus
Confidence Intervals
Insulin
Independent Living
Baltimore
Osteoporotic Fractures
Metformin
Hand Strength
Therapeutics
Prescriptions
Cohort Studies
Prospective Studies
Equipment and Supplies

Keywords

  • diabetes mellitus
  • elderly
  • insulin sensitizer
  • physical performance
  • walk speed

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Changes in physical performance in older women according to presence and treatment of diabetes mellitus. / Lee, Christine; Schwartz, Ann V.; Yaffe, Kristine; Hillier, Teresa A.; Leblanc, Erin S.; Cawthon, Peggy M.

In: Journal of the American Geriatrics Society, Vol. 61, No. 11, 11.2013, p. 1872-1878.

Research output: Contribution to journalArticle

Lee, Christine ; Schwartz, Ann V. ; Yaffe, Kristine ; Hillier, Teresa A. ; Leblanc, Erin S. ; Cawthon, Peggy M. / Changes in physical performance in older women according to presence and treatment of diabetes mellitus. In: Journal of the American Geriatrics Society. 2013 ; Vol. 61, No. 11. pp. 1872-1878.
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