Ceramic capillaries for use in microarray fabrication

R. A. George, J. P. Woolley, Paul Spellman

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We have used ceramic capillary tips generally used in the microelectronics industry for the production of DNA microarrays. The ceramic tips improve the morphology of microarray elements, allow higher element density, and increase printing tip life over the customary slotted stainless-steel pins. Ceramic tips are less expensive than steel pins and allow printing from 1536-well sample source plates. In this work, we describe experiments that establish printing performance of the ceramic tips and hybridization experiments that show that DNA hybridization is unaffected by the choice of tip material.

Original languageEnglish (US)
Pages (from-to)1780-1783
Number of pages4
JournalGenome Research
Volume11
Issue number10
DOIs
StatePublished - 2001
Externally publishedYes

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Ceramics
Printing
Steel
Stainless Steel
Oligonucleotide Array Sequence Analysis
Industry
DNA

ASJC Scopus subject areas

  • Genetics

Cite this

Ceramic capillaries for use in microarray fabrication. / George, R. A.; Woolley, J. P.; Spellman, Paul.

In: Genome Research, Vol. 11, No. 10, 2001, p. 1780-1783.

Research output: Contribution to journalArticle

George, R. A. ; Woolley, J. P. ; Spellman, Paul. / Ceramic capillaries for use in microarray fabrication. In: Genome Research. 2001 ; Vol. 11, No. 10. pp. 1780-1783.
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