Cariostasis by moderate doses of selenium in the rat model

J. L. Britton, Thomas (Tom) Shearer, D. J. DeSart

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The purpose of this study was to measure the effect of dietary selenium present during tooth development on dental caries. Ten-day pregnant rats received either distilled drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium or selenite or selenomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MIT-200 diet for 7 wk. Moderate levels (0.8 ppm) of developmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.

Original languageEnglish (US)
Pages (from-to)74-76
Number of pages3
JournalArchives of Environmental Health
Volume35
Issue number2
StatePublished - 1980

Fingerprint

Selenium
selenium
Rats
Rat control
Selenomethionine
Sodium Selenite
Selenious Acid
selenite
Cheek
Dental Caries
Nutrition
Drinking Water
tooth
Tooth
Sodium
drinking water
sodium
dose
diet
Diet

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health

Cite this

Cariostasis by moderate doses of selenium in the rat model. / Britton, J. L.; Shearer, Thomas (Tom); DeSart, D. J.

In: Archives of Environmental Health, Vol. 35, No. 2, 1980, p. 74-76.

Research output: Contribution to journalArticle

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