Cariostasis by moderate doses of selenium in the rat model

Jimi Britton; Thomas R. Shearer; Del J. Desart

doi:10.1080/00039896.1980.10667467

Cariostasis by moderate doses of selenium in the rat model

Jimi Britton, Thomas R. Shearer, Del J. Desart

Integrative Biosciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The purpose of this study was to measure the effect of dietary seienium present during tooth development on dental caries. Ten-day pregnant rats received either distilied drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium selenite or seienomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MiT -200 diet for 7 wk. Moderate levels (0.8 ppm) of deveiopmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.

Original language	English (US)
Pages (from-to)	74-76
Number of pages	3
Journal	Archives of Environmental Health
Volume	35
Issue number	2
DOIs	https://doi.org/10.1080/00039896.1980.10667467
State	Published - Mar 1980

ASJC Scopus subject areas

Environmental Chemistry
General Environmental Science
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

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10.1080/00039896.1980.10667467

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title = "Cariostasis by moderate doses of selenium in the rat model",

abstract = "The purpose of this study was to measure the effect of dietary seienium present during tooth development on dental caries. Ten-day pregnant rats received either distilied drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium selenite or seienomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MiT -200 diet for 7 wk. Moderate levels (0.8 ppm) of deveiopmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.",

author = "Jimi Britton and Shearer, {Thomas R.} and Desart, {Del J.}",

note = "Funding Information: This study was supported in part, by PHS grant numbers DE-03856 and DE-03536. Submitted for publication july 12, 1979; accepted for publication july 31, 1979. Requests for reprints should be addressed to: Dr. T. R. Shearer, University of Oregon Health Science Center, Portland, OR 97201.",

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doi = "10.1080/00039896.1980.10667467",

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T1 - Cariostasis by moderate doses of selenium in the rat model

AU - Britton, Jimi

AU - Shearer, Thomas R.

AU - Desart, Del J.

N1 - Funding Information: This study was supported in part, by PHS grant numbers DE-03856 and DE-03536. Submitted for publication july 12, 1979; accepted for publication july 31, 1979. Requests for reprints should be addressed to: Dr. T. R. Shearer, University of Oregon Health Science Center, Portland, OR 97201.

PY - 1980/3

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N2 - The purpose of this study was to measure the effect of dietary seienium present during tooth development on dental caries. Ten-day pregnant rats received either distilied drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium selenite or seienomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MiT -200 diet for 7 wk. Moderate levels (0.8 ppm) of deveiopmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.

AB - The purpose of this study was to measure the effect of dietary seienium present during tooth development on dental caries. Ten-day pregnant rats received either distilied drinking water or water containing 0.8 ppm or 2.4 ppm selenium, as sodium selenite or seienomethionine, until the pups were weaned. Buccal caries were measured in the pups after being fed a MiT -200 diet for 7 wk. Moderate levels (0.8 ppm) of deveiopmental selenium significantly reduced caries in male rats when compared to control rats or to rats receiving high levels of selenium (2.4 ppm). The results indicated that moderate doses of selenium were cariostatic.

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Cariostasis by moderate doses of selenium in the rat model

Abstract

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