Calibration of rotational acceleration for the rotarod test of rodent motor coordination

Martin Bohlen, Andy Cameron, Pamela Metten, John Jr Crabbe, Douglas Wahlsten

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The latency of mice and rats to fall from the accelerating rotarod can differ markedly between laboratories using the same brand of rod as well as between studies using different kinds of rods. These discrepancies can arise from different rod diameters, surface textures, test protocols, or laboratory environmental factors beyond the test itself, but it is also possible that the actual acceleration rates of the different rods do not correspond to the nominal rates set on the devices. This paper describes a simple method to measure acceleration rate of the rotarod and to set the rate to a desired value for any brand of rod.

Original languageEnglish (US)
Pages (from-to)10-14
Number of pages5
JournalJournal of Neuroscience Methods
Volume178
Issue number1
DOIs
StatePublished - Mar 30 2009

Fingerprint

Rotarod Performance Test
Calibration
Rodentia
Equipment and Supplies

Keywords

  • Behavioral test
  • Motor coordination
  • Mouse
  • Rat
  • Rotarod
  • Task parameters
  • Test standardization

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Calibration of rotational acceleration for the rotarod test of rodent motor coordination. / Bohlen, Martin; Cameron, Andy; Metten, Pamela; Crabbe, John Jr; Wahlsten, Douglas.

In: Journal of Neuroscience Methods, Vol. 178, No. 1, 30.03.2009, p. 10-14.

Research output: Contribution to journalArticle

Bohlen, Martin ; Cameron, Andy ; Metten, Pamela ; Crabbe, John Jr ; Wahlsten, Douglas. / Calibration of rotational acceleration for the rotarod test of rodent motor coordination. In: Journal of Neuroscience Methods. 2009 ; Vol. 178, No. 1. pp. 10-14.
@article{456cd78689d441bd8743037ea3d8dc35,
title = "Calibration of rotational acceleration for the rotarod test of rodent motor coordination",
abstract = "The latency of mice and rats to fall from the accelerating rotarod can differ markedly between laboratories using the same brand of rod as well as between studies using different kinds of rods. These discrepancies can arise from different rod diameters, surface textures, test protocols, or laboratory environmental factors beyond the test itself, but it is also possible that the actual acceleration rates of the different rods do not correspond to the nominal rates set on the devices. This paper describes a simple method to measure acceleration rate of the rotarod and to set the rate to a desired value for any brand of rod.",
keywords = "Behavioral test, Motor coordination, Mouse, Rat, Rotarod, Task parameters, Test standardization",
author = "Martin Bohlen and Andy Cameron and Pamela Metten and Crabbe, {John Jr} and Douglas Wahlsten",
year = "2009",
month = "3",
day = "30",
doi = "10.1016/j.jneumeth.2008.11.001",
language = "English (US)",
volume = "178",
pages = "10--14",
journal = "Journal of Neuroscience Methods",
issn = "0165-0270",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Calibration of rotational acceleration for the rotarod test of rodent motor coordination

AU - Bohlen, Martin

AU - Cameron, Andy

AU - Metten, Pamela

AU - Crabbe, John Jr

AU - Wahlsten, Douglas

PY - 2009/3/30

Y1 - 2009/3/30

N2 - The latency of mice and rats to fall from the accelerating rotarod can differ markedly between laboratories using the same brand of rod as well as between studies using different kinds of rods. These discrepancies can arise from different rod diameters, surface textures, test protocols, or laboratory environmental factors beyond the test itself, but it is also possible that the actual acceleration rates of the different rods do not correspond to the nominal rates set on the devices. This paper describes a simple method to measure acceleration rate of the rotarod and to set the rate to a desired value for any brand of rod.

AB - The latency of mice and rats to fall from the accelerating rotarod can differ markedly between laboratories using the same brand of rod as well as between studies using different kinds of rods. These discrepancies can arise from different rod diameters, surface textures, test protocols, or laboratory environmental factors beyond the test itself, but it is also possible that the actual acceleration rates of the different rods do not correspond to the nominal rates set on the devices. This paper describes a simple method to measure acceleration rate of the rotarod and to set the rate to a desired value for any brand of rod.

KW - Behavioral test

KW - Motor coordination

KW - Mouse

KW - Rat

KW - Rotarod

KW - Task parameters

KW - Test standardization

UR - http://www.scopus.com/inward/record.url?scp=59249109467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=59249109467&partnerID=8YFLogxK

U2 - 10.1016/j.jneumeth.2008.11.001

DO - 10.1016/j.jneumeth.2008.11.001

M3 - Article

C2 - 19041892

AN - SCOPUS:59249109467

VL - 178

SP - 10

EP - 14

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

IS - 1

ER -