Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

J. A. Kaye, M. M. Moore, D. Galasko, U. K. Craig, R. Adonay, L. C. Silbert

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI brain volumes differed between diagnostic groups (GD, PDC, control) and according to family history. Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders.

Original languageEnglish (US)
Pages (from-to)196-199
Number of pages4
JournalNeurology
Volume69
Issue number2
DOIs
StatePublished - Jul 1 2007

ASJC Scopus subject areas

  • Clinical Neurology

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