Brain steroid synthesis and metabolism

John A. Resko, Charles E. Roselli

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We describe two methods for quantifying key enzymes that metabolize testosterone to active metabolites within the central nervous system. These techniques are useful for investigating endocrine control of neural function by steroid hormones. We caution, however, that these assays must be validated in the individual laboratories in which they are used. Without validation, one cannot be sure of the reliability of the data that will be generated.

Original languageEnglish (US)
Pages (from-to)27-34
Number of pages8
Issue number1
StatePublished - Aug 1992


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