Biological laser action

Lihong Wang, Da Liu, Nancy He, Steven Jacques, Sharon L. Thomsen

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The narrowing of the spectral linewidth and the increasing of the peak intensity characteristic of laser action were observed in emission spectra of dye-infused biological tissues. The tissue was infused with a solution of Rhodamine 640 perchlorate in ethanol and then excited with frequency-doubled Q-switched Nd:YAG laser pulses. The dependence of emission linewidth on the excitation radiant exposure and dye concentration was investigated. Laser action was also observed in biologically compatible fluorescein sodium dye dissolved in phosphate-buffered saline mixed with scattering polystyrene spheres. The sharp spectral peaks of laser action in tissues may find applications in the detection of superficial disease.

Original languageEnglish (US)
Pages (from-to)1775-1779
Number of pages5
JournalApplied Optics
Volume35
Issue number10
StatePublished - Apr 1 1996
Externally publishedYes

Fingerprint

Dyes
dyes
Tissue
Linewidth
Lasers
lasers
Q switched lasers
perchlorates
rhodamine
YAG lasers
Laser pulses
Polystyrenes
polystyrene
phosphates
Phosphates
emission spectra
Ethanol
ethyl alcohol
Sodium
sodium

Keywords

  • Amplification of spontaneous emission
  • Fluorescence
  • Laser action
  • Tissue optics
  • Turbid media

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Wang, L., Liu, D., He, N., Jacques, S., & Thomsen, S. L. (1996). Biological laser action. Applied Optics, 35(10), 1775-1779.

Biological laser action. / Wang, Lihong; Liu, Da; He, Nancy; Jacques, Steven; Thomsen, Sharon L.

In: Applied Optics, Vol. 35, No. 10, 01.04.1996, p. 1775-1779.

Research output: Contribution to journalArticle

Wang, L, Liu, D, He, N, Jacques, S & Thomsen, SL 1996, 'Biological laser action', Applied Optics, vol. 35, no. 10, pp. 1775-1779.
Wang L, Liu D, He N, Jacques S, Thomsen SL. Biological laser action. Applied Optics. 1996 Apr 1;35(10):1775-1779.
Wang, Lihong ; Liu, Da ; He, Nancy ; Jacques, Steven ; Thomsen, Sharon L. / Biological laser action. In: Applied Optics. 1996 ; Vol. 35, No. 10. pp. 1775-1779.
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