Bilateral anterior uveitis associated with clomiphene citrate

Thomas D. Myers; Fredrick W. Fraunfelder

doi:10.1080/09273940701799155

Bilateral anterior uveitis associated with clomiphene citrate

Thomas D. Myers, Fredrick W. Fraunfelder

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Purpose: To report a case of bilateral anterior uveitis associated with ovulation induction therapy using clomiphene citrate. Design: Retrospective case review. Methods: A single patient who developed uveitis while taking clomiphene citrate is described. Results: A 30-year-old woman with polycystic ovary syndrome developed bilateral anterior uveitis during ovulation induction therapy. Results of laboratory studies were normal and the patient was treated with topical therapy. Upon rechallenge with clomiphene 3 months later, she again developed bilateral anterior uveitis. Conclusions: Ovulation induction therapy with clomiphene citrate may precipitate uveitis.

Original language	English (US)
Pages (from-to)	23-24
Number of pages	2
Journal	Ocular Immunology and Inflammation
Volume	16
Issue number	1-2
DOIs	https://doi.org/10.1080/09273940701799155
State	Published - Jan 2008
Externally published	Yes

Keywords

Clomiphene citrate
Ocular inflammation
Ovulation induction therapy
Polycystic ovary syndrome
Uveitis

ASJC Scopus subject areas

Immunology and Allergy
Ophthalmology

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10.1080/09273940701799155

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title = "Bilateral anterior uveitis associated with clomiphene citrate",

abstract = "Purpose: To report a case of bilateral anterior uveitis associated with ovulation induction therapy using clomiphene citrate. Design: Retrospective case review. Methods: A single patient who developed uveitis while taking clomiphene citrate is described. Results: A 30-year-old woman with polycystic ovary syndrome developed bilateral anterior uveitis during ovulation induction therapy. Results of laboratory studies were normal and the patient was treated with topical therapy. Upon rechallenge with clomiphene 3 months later, she again developed bilateral anterior uveitis. Conclusions: Ovulation induction therapy with clomiphene citrate may precipitate uveitis.",

keywords = "Clomiphene citrate, Ocular inflammation, Ovulation induction therapy, Polycystic ovary syndrome, Uveitis",

author = "Myers, {Thomas D.} and Fraunfelder, {Fredrick W.}",

note = "Funding Information: Received 3 August, 2007; accepted 7 October, 2007. This study was supported in part by an unrestricted grant to Casey Eye Institute from Research to Prevent Blindness, New York, NY, and by the National Registry of Drug-Induced Ocular Side Effects, Casey Eye Institute, Oregon Health & Science University, Portland, OR. The authors are indebted to the national centers in this study that contributed data. However, the opinions and conclusions expressed are not necessarily those of the FDA or the WHO. Thanks to Genevieve J. Long, PhD, for editing assistance. Correspondence and reprint requests to: F.W. Fraunfelder, MD, Casey Eye Institute, 3375 SW Terwilliger Blvd, Portland, OR 97239-4197, USA. E-mail: eyedrug@ohsu.edu",

year = "2008",

month = jan,

doi = "10.1080/09273940701799155",

language = "English (US)",

volume = "16",

pages = "23--24",

journal = "Ocular Immunology and Inflammation",

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T1 - Bilateral anterior uveitis associated with clomiphene citrate

AU - Myers, Thomas D.

AU - Fraunfelder, Fredrick W.

N1 - Funding Information: Received 3 August, 2007; accepted 7 October, 2007. This study was supported in part by an unrestricted grant to Casey Eye Institute from Research to Prevent Blindness, New York, NY, and by the National Registry of Drug-Induced Ocular Side Effects, Casey Eye Institute, Oregon Health & Science University, Portland, OR. The authors are indebted to the national centers in this study that contributed data. However, the opinions and conclusions expressed are not necessarily those of the FDA or the WHO. Thanks to Genevieve J. Long, PhD, for editing assistance. Correspondence and reprint requests to: F.W. Fraunfelder, MD, Casey Eye Institute, 3375 SW Terwilliger Blvd, Portland, OR 97239-4197, USA. E-mail: eyedrug@ohsu.edu

PY - 2008/1

Y1 - 2008/1

N2 - Purpose: To report a case of bilateral anterior uveitis associated with ovulation induction therapy using clomiphene citrate. Design: Retrospective case review. Methods: A single patient who developed uveitis while taking clomiphene citrate is described. Results: A 30-year-old woman with polycystic ovary syndrome developed bilateral anterior uveitis during ovulation induction therapy. Results of laboratory studies were normal and the patient was treated with topical therapy. Upon rechallenge with clomiphene 3 months later, she again developed bilateral anterior uveitis. Conclusions: Ovulation induction therapy with clomiphene citrate may precipitate uveitis.

AB - Purpose: To report a case of bilateral anterior uveitis associated with ovulation induction therapy using clomiphene citrate. Design: Retrospective case review. Methods: A single patient who developed uveitis while taking clomiphene citrate is described. Results: A 30-year-old woman with polycystic ovary syndrome developed bilateral anterior uveitis during ovulation induction therapy. Results of laboratory studies were normal and the patient was treated with topical therapy. Upon rechallenge with clomiphene 3 months later, she again developed bilateral anterior uveitis. Conclusions: Ovulation induction therapy with clomiphene citrate may precipitate uveitis.

KW - Clomiphene citrate

KW - Ocular inflammation

KW - Ovulation induction therapy

KW - Polycystic ovary syndrome

KW - Uveitis

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Bilateral anterior uveitis associated with clomiphene citrate

Abstract

Keywords

ASJC Scopus subject areas

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