Beyond Frontiers: Feasibility and Outcomes of Prolonged Veno-Venous Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome

Ahmed A. Rabie, Ayed Asiri, Mostafa Rajab, Hani N. Mufti, Medhat Alsherbiny, Mohamed H. Azzam, Akram Abdelbary, Bishoy Zakhary, Yaseen Arabi, Abdulrahman Alharthy, Mohamed Futaih, Mohamed Sobhy, Ismael Alenazi, Fahad Bafaqeeh

Research output: Contribution to journalArticlepeer-review

Abstract

Extracorporeal membrane oxygenation (ECMO) use in acute respiratory failure is increasing. We aim to compare characteristics and outcomes of patients with prolonged (≥21 days) veno-venous (VV) ECMO runs (pECMO), to patients with short (<21 days) VV ECMO runs (sECMO). The observational retrospective single-center study compared patients who received VV ECMO from January 2018 to June 2019 at Prince Mohamed Bin Abdulaziz Center in Riyadh, Saudi Arabia. Forty-three patients were supported with VV ECMO during the study period, of whom 37 are included as six patients were still receiving ECMO at time of data collection: 24 sECMO and 13 pECMO patients. Baseline characteristics and comorbidities were similar except pECMO patients were older and had a lower P/F ratio (61 [58-68] vs. 71[58-85.5], p = 0.05). Survival to hospital discharge (69% vs. 83%, p = 0.32; pECMO vs. sECMO) and 90 day survival (62% vs. 75%, p = 0.413; pECMO vs. sECMO) were similar among groups. At 1 year follow-up, all patients were still alive and independently functioning except for one patient in the pECMO group who required a walking aid related to trauma. In this single-center study, patients requiring pECMO had similar short- and long-term survival to those requiring sECMO duration.

Original languageEnglish (US)
Pages (from-to)339-344
Number of pages6
JournalASAIO Journal
DOIs
StatePublished - Mar 1 2021

Keywords

  • extended ECMO
  • long-term ECMO
  • prolonged ECMO
  • severe acute respiratory distress syndrome
  • veno-venous extracorporeal membrane oxygenation

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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