BEHAVIORAL AND ELECTROGRAPHIC ANALYSIS OF PENICILLIN-INDUCED GENERALIZED SPIKE-WAVE DISCHARGES IN THE CAT.

Kim J. Burchiel, Robert R. Myers, James J. Stockard, Reginald G. Bickford

Research output: Contribution to conferencePaper

1 Scopus citations

Abstract

The purpose of this work is to investigate the electrographic nature of one animal model of experimentally-induced spike-wave, its behavorial correlates and its implications and feasibility as a model of petit mal epilepsy. The obvious behavioral and electrographic manifestations of the above model bear a close resemblance to classical human petit mal, and although it could be argued that there are certain differences, for instance in the frequency of the spike-waves, these could be explained by interspecific differences in a fundamentally similar mechanism of epileptogenesis. Equally important are the insights which this model may provide into the pathophysiology of EEG synchronization as it relates to other forms of human epilepsy such as grand mal and myoclonic epilepsy.

Original languageEnglish (US)
Pages175-179
Number of pages5
StatePublished - Jan 1 1974
EventSan Diego Biomed Symp, Proc - San Diego, CA, USA
Duration: Feb 6 1974Feb 8 1974

Other

OtherSan Diego Biomed Symp, Proc
CitySan Diego, CA, USA
Period2/6/742/8/74

ASJC Scopus subject areas

  • Engineering(all)

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    Burchiel, K. J., Myers, R. R., Stockard, J. J., & Bickford, R. G. (1974). BEHAVIORAL AND ELECTROGRAPHIC ANALYSIS OF PENICILLIN-INDUCED GENERALIZED SPIKE-WAVE DISCHARGES IN THE CAT.. 175-179. Paper presented at San Diego Biomed Symp, Proc, San Diego, CA, USA, .