Automated detection of shadow artifacts in optical coherence tomography angiography

Acner Camino, Jia Yali, Jeffrey Yu, Jie Wang, Liang Liu, David Huang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Frequently, when imaging retinal vasculature with optical coherence tomography angiography (OCTA) in diseased eyes, there are unavoidable obstacles to the propagation of light such as vitreous floaters or the pupil boundary. These obstacles can block the optical coherence tomography (OCT) beam and impede the visualization of the underlying retinal microcirculation. Detecting these shadow artifacts is especially important in the quantification of metrics that assess retinal disease progression because they might masquerade as regional perfusion loss. In this work, we present an algorithm to identify shadowed areas in OCTA of healthy subjects as well as patients with diabetic retinopathy, uveitis and age-related macular degeneration. The aim is to exclude these areas from analysis so that the overall OCTA parameters are minimally affected by shadow artifacts.

Original languageEnglish (US)
Article number#357543
Pages (from-to)1514-1531
Number of pages18
JournalBiomedical Optics Express
Volume10
Issue number3
DOIs
StatePublished - Mar 1 2019

Fingerprint

angiography
Optical Coherence Tomography
Artifacts
artifacts
Angiography
tomography
Retinal Diseases
degeneration
Eye Diseases
Uveitis
Macular Degeneration
Diabetic Retinopathy
pupils
Microcirculation
Pupil
progressions
Disease Progression
Healthy Volunteers
Perfusion
Light

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Cite this

Automated detection of shadow artifacts in optical coherence tomography angiography. / Camino, Acner; Yali, Jia; Yu, Jeffrey; Wang, Jie; Liu, Liang; Huang, David.

In: Biomedical Optics Express, Vol. 10, No. 3, #357543, 01.03.2019, p. 1514-1531.

Research output: Contribution to journalArticle

Camino, Acner ; Yali, Jia ; Yu, Jeffrey ; Wang, Jie ; Liu, Liang ; Huang, David. / Automated detection of shadow artifacts in optical coherence tomography angiography. In: Biomedical Optics Express. 2019 ; Vol. 10, No. 3. pp. 1514-1531.
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