Automated detection of dilated capillaries on optical coherence tomography angiography

Changlei Dongye, Miao Zhang, Thomas S. Hwang, Jie Wang, Simon S. Gao, Liang Liu, David Huang, David J. Wilson, Yali Jia

Research output: Research - peer-reviewArticle

  • 1 Citations

Abstract

Automated detection and grading of angiographic high-risk features in diabetic retinopathy can potentially enhance screening and clinical care. We have previously identified capillary dilation in angiograms of the deep plexus in optical coherence tomography angiography as a feature associated with severe diabetic retinopathy. In this study, we present an automated algorithm that uses hybrid contrast to distinguish angiograms with dilated capillaries from healthy controls and then applies saliency measurement to map the extent of the dilated capillary networks. The proposed algorithm agreed well with human grading.

LanguageEnglish (US)
Article number#279084
Pages1101-1109
Number of pages9
JournalBiomedical Optics Express
Volume8
Issue number2
DOIs
StatePublished - Feb 1 2017

Fingerprint

Optical Coherence Tomography
Angiography
angiography
tomography
Diabetic Retinopathy
Dilatation
screening

Keywords

  • Image analysis
  • Image processing
  • Medical and biological imaging
  • Ophthalmology
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Cite this

Automated detection of dilated capillaries on optical coherence tomography angiography. / Dongye, Changlei; Zhang, Miao; Hwang, Thomas S.; Wang, Jie; Gao, Simon S.; Liu, Liang; Huang, David; Wilson, David J.; Jia, Yali.

In: Biomedical Optics Express, Vol. 8, No. 2, #279084, 01.02.2017, p. 1101-1109.

Research output: Research - peer-reviewArticle

Dongye C, Zhang M, Hwang TS, Wang J, Gao SS, Liu L et al. Automated detection of dilated capillaries on optical coherence tomography angiography. Biomedical Optics Express. 2017 Feb 1;8(2):1101-1109. #279084. Available from, DOI: 10.1364/BOE.8.001101
Dongye, Changlei ; Zhang, Miao ; Hwang, Thomas S. ; Wang, Jie ; Gao, Simon S. ; Liu, Liang ; Huang, David ; Wilson, David J. ; Jia, Yali. / Automated detection of dilated capillaries on optical coherence tomography angiography. In: Biomedical Optics Express. 2017 ; Vol. 8, No. 2. pp. 1101-1109
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