Autoimmune neutropenia as a cause of periodontal disease in preschool children

Evlambia Hajishengallis, Stephanie Rashewsky, Cyelee Kulkarni, Panagiota Stathopoulou

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


In autoimmune neutropenia, autoantibodies attack neutrophils resulting in their destruction or alteration of their function. Since neutrophils have important immunologic functions, aberrations in their homeostasis lead to increased susceptibility to diseases, such as periodontitis. Periodontitis as a manifestation of neutropenia can affect adults and children. In this paper, we describe the treatment of periodontal disease in a 2-year-old female with autoimmune neutropenia. The importance of an interdisciplinary approach, frequent recalls, and meticulous mechanical therapy in stabilizing her periodontal condition, despite ongoing systemic infections is emphasized.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalJournal of Clinical Pediatric Dentistry
Issue number1
StatePublished - 2016
Externally publishedYes


  • Autoimmune neutropenia
  • Children
  • Periodontal disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dentistry(all)


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