Asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum (AVID)

An imaging triad

Karen Oh, Anne M. Kennedy, Nathan Selden, Logan McLean, Roya Sohaey

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A series of 20 cases from 2 academic institutions is presented with a characteristic imaging triad of asymmetric ventriculomegaly, a large interhemispheric cyst, and partial or complete agenesis of the corpus callosum. Most cases were initially referred as aqueduct stenosis and hydrocephalus or focal porencephaly. We describe the imaging findings that identify an abnormal or absent corpus callosum associated with a type 1 interhemispheric cyst in fetuses initially thought to have hydrocephalus attributable to aqueductal stenosis. We suggest that the acronym AVID (asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum) may be useful in recognition of these cases. All cases presented with markedly asymmetric ventriculomegaly on initial sonography, with progressive hydrocephalus throughout gestation. Fetal magnetic resonance imaging was performed in 15 of 20 cases. Thirteen of 20 cases were identified in male fetuses. Associated fetal and postnatal abnormalities are also reported. Technological improvements in sonography and fetal magnetic resonance imaging allow improved characterization of associated intracranial anomalies in the setting of hydrocephalus. Accurate diagnosis can aid parental counseling, especially because isolated aqueductal stenosis suggests a better prognosis than hydrocephalus with anomalies. Markedly asymmetric ventriculomegaly in this series was the key to excluding isolated aqueductal stenosis and was associated with callosal malformation with a type 1a interhemispheric cyst.

Original languageEnglish (US)
Pages (from-to)1811-1820
Number of pages10
JournalJournal of Ultrasound in Medicine
Volume31
Issue number11
StatePublished - Nov 1 2012

Fingerprint

Agenesis of Corpus Callosum
Hydrocephalus
Cysts
Ultrasonography
Fetus
Magnetic Resonance Imaging
Corpus Callosum
Counseling
Pathologic Constriction
Pregnancy

Keywords

  • Asymmetric ventriculomegaly
  • Corpus callosum
  • Glioependymal cyst
  • Hydrocephalus
  • Interhemispheric cyst
  • Macrocephaly

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

Cite this

Asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum (AVID) : An imaging triad. / Oh, Karen; Kennedy, Anne M.; Selden, Nathan; McLean, Logan; Sohaey, Roya.

In: Journal of Ultrasound in Medicine, Vol. 31, No. 11, 01.11.2012, p. 1811-1820.

Research output: Contribution to journalArticle

@article{d92857808d1d443d95e2731da06fe0dd,
title = "Asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum (AVID): An imaging triad",
abstract = "A series of 20 cases from 2 academic institutions is presented with a characteristic imaging triad of asymmetric ventriculomegaly, a large interhemispheric cyst, and partial or complete agenesis of the corpus callosum. Most cases were initially referred as aqueduct stenosis and hydrocephalus or focal porencephaly. We describe the imaging findings that identify an abnormal or absent corpus callosum associated with a type 1 interhemispheric cyst in fetuses initially thought to have hydrocephalus attributable to aqueductal stenosis. We suggest that the acronym AVID (asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum) may be useful in recognition of these cases. All cases presented with markedly asymmetric ventriculomegaly on initial sonography, with progressive hydrocephalus throughout gestation. Fetal magnetic resonance imaging was performed in 15 of 20 cases. Thirteen of 20 cases were identified in male fetuses. Associated fetal and postnatal abnormalities are also reported. Technological improvements in sonography and fetal magnetic resonance imaging allow improved characterization of associated intracranial anomalies in the setting of hydrocephalus. Accurate diagnosis can aid parental counseling, especially because isolated aqueductal stenosis suggests a better prognosis than hydrocephalus with anomalies. Markedly asymmetric ventriculomegaly in this series was the key to excluding isolated aqueductal stenosis and was associated with callosal malformation with a type 1a interhemispheric cyst.",
keywords = "Asymmetric ventriculomegaly, Corpus callosum, Glioependymal cyst, Hydrocephalus, Interhemispheric cyst, Macrocephaly",
author = "Karen Oh and Kennedy, {Anne M.} and Nathan Selden and Logan McLean and Roya Sohaey",
year = "2012",
month = "11",
day = "1",
language = "English (US)",
volume = "31",
pages = "1811--1820",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "11",

}

TY - JOUR

T1 - Asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum (AVID)

T2 - An imaging triad

AU - Oh, Karen

AU - Kennedy, Anne M.

AU - Selden, Nathan

AU - McLean, Logan

AU - Sohaey, Roya

PY - 2012/11/1

Y1 - 2012/11/1

N2 - A series of 20 cases from 2 academic institutions is presented with a characteristic imaging triad of asymmetric ventriculomegaly, a large interhemispheric cyst, and partial or complete agenesis of the corpus callosum. Most cases were initially referred as aqueduct stenosis and hydrocephalus or focal porencephaly. We describe the imaging findings that identify an abnormal or absent corpus callosum associated with a type 1 interhemispheric cyst in fetuses initially thought to have hydrocephalus attributable to aqueductal stenosis. We suggest that the acronym AVID (asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum) may be useful in recognition of these cases. All cases presented with markedly asymmetric ventriculomegaly on initial sonography, with progressive hydrocephalus throughout gestation. Fetal magnetic resonance imaging was performed in 15 of 20 cases. Thirteen of 20 cases were identified in male fetuses. Associated fetal and postnatal abnormalities are also reported. Technological improvements in sonography and fetal magnetic resonance imaging allow improved characterization of associated intracranial anomalies in the setting of hydrocephalus. Accurate diagnosis can aid parental counseling, especially because isolated aqueductal stenosis suggests a better prognosis than hydrocephalus with anomalies. Markedly asymmetric ventriculomegaly in this series was the key to excluding isolated aqueductal stenosis and was associated with callosal malformation with a type 1a interhemispheric cyst.

AB - A series of 20 cases from 2 academic institutions is presented with a characteristic imaging triad of asymmetric ventriculomegaly, a large interhemispheric cyst, and partial or complete agenesis of the corpus callosum. Most cases were initially referred as aqueduct stenosis and hydrocephalus or focal porencephaly. We describe the imaging findings that identify an abnormal or absent corpus callosum associated with a type 1 interhemispheric cyst in fetuses initially thought to have hydrocephalus attributable to aqueductal stenosis. We suggest that the acronym AVID (asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum) may be useful in recognition of these cases. All cases presented with markedly asymmetric ventriculomegaly on initial sonography, with progressive hydrocephalus throughout gestation. Fetal magnetic resonance imaging was performed in 15 of 20 cases. Thirteen of 20 cases were identified in male fetuses. Associated fetal and postnatal abnormalities are also reported. Technological improvements in sonography and fetal magnetic resonance imaging allow improved characterization of associated intracranial anomalies in the setting of hydrocephalus. Accurate diagnosis can aid parental counseling, especially because isolated aqueductal stenosis suggests a better prognosis than hydrocephalus with anomalies. Markedly asymmetric ventriculomegaly in this series was the key to excluding isolated aqueductal stenosis and was associated with callosal malformation with a type 1a interhemispheric cyst.

KW - Asymmetric ventriculomegaly

KW - Corpus callosum

KW - Glioependymal cyst

KW - Hydrocephalus

KW - Interhemispheric cyst

KW - Macrocephaly

UR - http://www.scopus.com/inward/record.url?scp=84868096850&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868096850&partnerID=8YFLogxK

M3 - Article

VL - 31

SP - 1811

EP - 1820

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

SN - 0278-4297

IS - 11

ER -