@article{ecefcdf8c19b49399507a448b00a7ede,
title = "Associations of Pregnancy After Bariatric Surgery with Long-Term Weight Trajectories and Birth Weight: LABS-2 Study",
abstract = "Objective: This study aimed to examine whether pregnancy following bariatric surgery affects long-term maternal weight change and offspring birth weight. Methods: Using data from the Longitudinal Assessment of Bariatric Surgery (LABS)-2 study, linear regression was used to evaluate percent change in total body weight over a 5-year follow-up period among reproductive-aged women who underwent Roux-en-Y gastric bypass or laparoscopic adjustable gastric banding as well as evaluate the association of bariatric procedure type and offspring birth weight. Results: Of 727 women with preoperative age of 36.1 (6.3) years (mean [SD]) and BMI of 46.9 (7.0) kg/m2, 80 (11%) reported at least one pregnancy. After adjusting for covariates, percent change in total body weight was not significantly different between women who became pregnant and those who did not during a 5-year follow-up period (β = 2.02; 95% CI: −1.03 to 5.07; P = 0.19). Additionally, mean birth weight was not significantly different between mothers who underwent Roux-en-Y gastric bypass versus laparoscopic adjustable gastric banding (P = 0.99). Conclusions: Postoperative pregnancy did not diminish long-term weight loss in women in the LABS-2 study. The finding of comparable weight loss is relevant for providers counseling women of reproductive age on weight-loss expectations and family planning following bariatric surgery.",
author = "Harrod, {Curtis S.} and Elman, {Miriam R.} and Vesco, {Kimberly K.} and Wolfe, {Bruce M.} and Mitchell, {James E.} and Pories, {Walter J.} and Alfons Pomp and Janne Boone-Heinonen and Purnell, {Jonathan Q.}",
note = "Funding Information: This study was a cooperative agreement funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), with grant numbers as follows. DCC‐U01 DK066557; Columbia‐Presbyterian: U01‐DK66667 (in collaboration with Cornell University Medical Center Clinical and Translational Science Center [CTSC], grant UL1‐RR024996); University of Washington: U01‐DK66568 (in collaboration with Clinical and Translational Research Center [CTRC], grant M01RR‐00037); Neuropsychiatric Research Institute: U01‐DK66471; East Carolina University: U01‐DK66526; University of Pittsburgh Medical Center: U01‐DK66585 (in collaboration with CTRC, grant UL1‐RR024153); and Oregon Health & Science University: U01‐DK66555. Statistical support was provided in part by Oregon Health & Science University{\textquoteright}s School of Medicine Core Pilot Awards. Funding Information: BMW has received consultant fees from Enteromedics. JEM serves on the Shire International Advisory Board and receives royalties from Routledge and Guilford Press. WJP has received research grants from Johnson & Johnson and Janssen Pharmaceuticals. AP is a consultant and speaker for Medtronic, Ethicon, and W.L. Gore and Associates. The other authors reported no conflict of interest. Publisher Copyright: {\textcopyright} 2020 The Obesity Society Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = nov,
day = "1",
doi = "10.1002/oby.22944",
language = "English (US)",
volume = "28",
pages = "2209--2215",
journal = "Obesity",
issn = "1930-7381",
publisher = "Wiley-Blackwell",
number = "11",
}