Assessment of joint interactions between respiration and baroreflex activity using joint symbolic dynamics in heart failure patients

Muammar M. Kabir, Elyar Ghafoori, Larisa G. Tereshchenko

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Scopus citations

    Abstract

    In this paper we employed a novel approach based on joint symbolic dynamics (JSD) to study interaction between respiratory phase and baroreflex activity. Electrocardiogram (ECG) and blood pressure recordings from six participants with history of heart failure were included in this study. First, the ECG R-peaks and systolic blood pressure indices were detected using parabolic fitting. Second, the respiratory signal was derived from Frank orthogonal ECG leads using QRS slopes and R-wave angles. Third, time series of R-R intervals and systolic blood pressure (SBP) were extracted, and respiratory phases were obtained using the Hilbert transform. Subsequently, each series was transformed into binary symbol vectors based on their successive changes and words of length '2' were formed. Baroreflex patterns were studied using word combinations representing baroreflex activity for specific changes in respiratory phases. Baroreflex activity was significantly higher for alternating low-high/high-low heart rate and SBP during inspiration as compared to continuous increase or decrease in heart rate and SBP (wiSBP=10,wiHR=01,wRP=11: 39.1±9.3% vs. wiSBP=00,wiHR=11,wRP=11: 6.4±3.9%, p<0.0001).

    Original languageEnglish (US)
    Title of host publicationComputing in Cardiology Conference 2015, CinC 2015
    EditorsAlan Murray
    PublisherIEEE Computer Society
    Pages809-812
    Number of pages4
    ISBN (Electronic)9781509006854
    DOIs
    StatePublished - Feb 16 2015
    Event42nd Computing in Cardiology Conference, CinC 2015 - Nice, France
    Duration: Sep 6 2015Sep 9 2015

    Publication series

    NameComputing in Cardiology
    Volume42
    ISSN (Print)2325-8861
    ISSN (Electronic)2325-887X

    Other

    Other42nd Computing in Cardiology Conference, CinC 2015
    CountryFrance
    CityNice
    Period9/6/159/9/15

    ASJC Scopus subject areas

    • Computer Science(all)
    • Cardiology and Cardiovascular Medicine

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  • Cite this

    Kabir, M. M., Ghafoori, E., & Tereshchenko, L. G. (2015). Assessment of joint interactions between respiration and baroreflex activity using joint symbolic dynamics in heart failure patients. In A. Murray (Ed.), Computing in Cardiology Conference 2015, CinC 2015 (pp. 809-812). [7411034] (Computing in Cardiology; Vol. 42). IEEE Computer Society. https://doi.org/10.1109/CIC.2015.7411034