Anticoagulation in the cardiac patient: A concise review

Elise A. Larson, David M. German, Joseph Shatzel, Thomas G. DeLoughery

    Research output: Contribution to journalReview articlepeer-review

    1 Scopus citations


    Anticoagulation has multiple roles in the treatment of cardiovascular disease, including in management of acute myocardial infarction, during percutaneous coronary intervention, as stroke prophylaxis in patients with atrial arrhythmias, and in patients with mechanical heart valves. Clinical anticoagulation choices in the aforementioned diseases vary widely, due to conflicting data to support established agents and the rapid evolution of evidence-based practice that parallels more widespread use of novel oral anticoagulants. This review concisely summarizes evidence-based guidelines for anticoagulant use in cardiovascular disease, and highlights new data specific to direct oral anticoagulants.

    Original languageEnglish (US)
    Pages (from-to)3-19
    Number of pages17
    JournalEuropean Journal of Haematology
    Issue number1
    StatePublished - Jan 2019


    • anticoagulation
    • atrial fibrillation
    • cardiovascular disease
    • direct oral anticoagulants
    • novel oral anticoagulants
    • nste-acs

    ASJC Scopus subject areas

    • Hematology

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