Antibiotic use in premature infants after discharge from the neonatal intensive care unit

Scott A. Lorch, Kelly C. Wade, Susan Bakewell-Sachs, Barbara Medoff-Cooper, Jeffrey H. Silber, Gabriel J. Escobar

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Using a retrospective cohort of premature infants, we constructed multivariable Poisson models to determine factors associated with the receipt of antibiotics during the first year after discharge, N = 891. Black race (incidence rate ratio 1.80 compared with White infants, P =.008), male gender (incidence rate ratio 1.44; P =.007), bronchopulmonary dysplasia (incidence rate ratio 1.47; P =.04), and each additional child at home (incidence rate ratio 1.21, P =.002) increased the receipt of antibiotics for any reason. Male gender and additional children at home increased the receipt of nonrecommended antibiotics, while Black infants received care at facilities that prescribed more nonrecommended antibiotics. Even in a high-risk population of children, factors other than the medical history and presentation of the child may alter antibiotic prescription patterns and result in variations in care.

Original languageEnglish (US)
Pages (from-to)249-257
Number of pages9
JournalClinical pediatrics
Volume49
Issue number3
DOIs
StatePublished - Apr 2010
Externally publishedYes

Keywords

  • Antibiotics
  • Premature infants
  • Quality of care

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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