Angiomatoid melanoma: A case of metastatic melanoma mimicking a vascular malignancy

Michael J. Adler, Jay Beckstead, Clifton R. White

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

We present a case of melanoma metastatic to forehead skin and sacral vertebra, without known primary, which, in the cutaneous metastasis, displayed striking histologic features suggesting vascular differentiation. Histopathologic examination of the lesion revealed a large, deeply extending spindle cell malignancy with numerous, cavernous, erythrocyte-filled spaces throughout and only scant melanin pigmentation, making initial diagnosis challenging. The neoplastic cells demonstrated positive staining with antibodies to S-100 protein, HMB 45, and vimentin. We suggest the term angiomatoid melanoma for this histopathologic variant.

Original languageEnglish (US)
Pages (from-to)606-609
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume19
Issue number6
DOIs
StatePublished - Dec 12 1997

Keywords

  • Angiomatoid metastatic melanoma
  • Malignancy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Fingerprint Dive into the research topics of 'Angiomatoid melanoma: A case of metastatic melanoma mimicking a vascular malignancy'. Together they form a unique fingerprint.

  • Cite this