Androgens and bone growth: It's location, location, location

Kristine M. Wiren

Research output: Contribution to journalReview article

34 Scopus citations

Abstract

Androgens increase bone mass in specific skeletal compartments through effects on bone cells, enhancing osteoblast activity but inhibiting that of osteoclasts. The mechanism of action of androgens might involve both classic androgen receptor transcriptional activation and rapid non-genomic effects, and could also be dependent upon low levels of estrogen.

Original languageEnglish (US)
Pages (from-to)626-632
Number of pages7
JournalCurrent Opinion in Pharmacology
Volume5
Issue number6 SPEC. ISS.
DOIs
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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