Abstract
A variety of methods and algorithms have recently been employed in the analysis of gene expression data, including reverseengineering and knowledge-based pathway modeling, semantic gene similarity, network analysis and clustering. These methods and algorithms address different subparts of the same overall challenge and need to be applied in combination to address predictive genomic analysis as a whole. In this paper, we present an integrated approach to predictive genomic analysis that achieves this objective and describe an application of the approach to the study of neuroprotection in stroke.
Original language | English (US) |
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Title of host publication | 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010 |
Pages | 390-393 |
Number of pages | 4 |
DOIs | |
State | Published - 2010 |
Externally published | Yes |
Event | 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010 - Niagara Falls, NY, United States Duration: Aug 2 2010 → Aug 4 2010 |
Publication series
Name | 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010 |
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Other
Other | 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010 |
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Country/Territory | United States |
City | Niagara Falls, NY |
Period | 8/2/10 → 8/4/10 |
Keywords
- Biological pathways
- Gene clustering
- Gene ontology
- Gene similarity
- Pathway inference
- Predictive pathway analysis
ASJC Scopus subject areas
- Biomedical Engineering
- Health Information Management