An Experimental and Computational Evolution-Based Method to Study a Mode of Co-evolution of Overlapping Open Reading Frames in the AAV2 Viral Genome

Medicine & Life Sciences

• Viral Genome 100%
• Open Reading Frames 84%
• Adeno-associated virus-2 33%
• Proteins 32%
• Amino Acid Motifs 28%
• Sequence Alignment 26%
• Valine 26%
• Capsid 25%
• Capsid Proteins 25%
• Sequence Homology 24%
• Mutant Proteins 23%
• Serine 21%
• High-Throughput Nucleotide Sequencing 21%
• Computer Simulation 20%
• Serogroup 20%
• Datasets 17%
• Amino Acids 15%

Agriculture & Biology

• coevolution 96%
• open reading frames 70%
• genome 48%
• mutants 41%
• proteins 29%
• Dependoparvovirus 27%
• directed evolution 24%
• methodology 23%
• nucleotide sequences 22%
• capsid 20%
• sequence alignment 18%
• coat proteins 17%
• sequence homology 16%
• serotypes 15%
• viability 13%
• amino acid sequences 12%
• amino acids 9%

Chemical Compounds

• Protein 36%
• Nucleotide Sequence 36%
• Valine 16%
• Serine 13%
• Shape 9%
• Acid 5%
• Application 4%