Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis

Julie T. Crawford, Leonardo Pereira, John Buckmaster, Michael G. Gravett, Jorge E. Tolosa

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

We report a case of subclinical Candida albicans chorioamnionitis with mid-trimester cervical dilation diagnosed by amniotic fluid culture and Gram stain. Proteomic analysis of amniotic fluid demonstrated protein biomarkers previously associated only with bacterial intra-amniotic infections. We hypothesize that since amniotic fluid culture of yeast may take days, novel tests such as proteomic profiling may lead to the development of rapid diagnostic tests for fungal intra-amniotic infections.

Original languageEnglish (US)
Pages (from-to)667-670
Number of pages4
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume19
Issue number10
DOIs
StatePublished - Oct 1 2006

Keywords

  • Amniocentesis
  • Candidal infection
  • Chorioamnionitis
  • Proteomics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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