American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography

Sharon L. Mulvagh, Harry Rakowski, Mani A. Vannan, Sahar S. Abdelmoneim, Harald Becher, S. Michelle Bierig, Peter N. Burns, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Dalane W. Kitzman, Itzhak Kronzon, Arthur J. Labovitz, Roberto M. Lang, Joseph Mathew, W. Stuart Moir, Sherif F. Nagueh, Alan S. PearlmanJulio E. Perez, Thomas R. Porter, Judy Rosenbloom, G. Monet Strachan, Srihari Thanigaraj, Kevin Wei, Anna Woo, Eric H C Yu, William A. Zoghbi

    Research output: Contribution to journalArticle

    302 Citations (Scopus)

    Abstract

    Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

    Original languageEnglish (US)
    Pages (from-to)1179-1201
    Number of pages23
    JournalJournal of the American Society of Echocardiography
    Volume21
    Issue number11
    DOIs
    StatePublished - Nov 2008

    Fingerprint

    Diagnostic Imaging
    Ultrasonics
    Contrast Media
    Echocardiography
    Consultants
    Consensus
    Organized Financing
    Research
    Conflict of Interest
    Continuing Medical Education
    Disclosure
    Accreditation
    Physicians
    Equipment and Supplies
    Registries
    Guidelines
    Credentialing
    Delivery of Health Care
    Safety
    Stress Echocardiography

    Keywords

    • Cardiac imaging
    • Contrast echocardiography
    • Contrast microbubbles
    • Coronary artery disease
    • Echocardiography
    • Endocardial border definition
    • Left ventricular ejection fraction
    • Left ventricular opacification
    • Myocardial contrast echocardiography
    • Myocardial perfusion imaging
    • Power Doppler imaging
    • Real-time contrast echocardiography
    • Stress echocardiography
    • Ultrasound contrast agents
    • Wall motion analysis

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging
    • Cardiology and Cardiovascular Medicine

    Cite this

    American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. / Mulvagh, Sharon L.; Rakowski, Harry; Vannan, Mani A.; Abdelmoneim, Sahar S.; Becher, Harald; Bierig, S. Michelle; Burns, Peter N.; Castello, Ramon; Coon, Patrick D.; Hagen, Mary E.; Jollis, James G.; Kimball, Thomas R.; Kitzman, Dalane W.; Kronzon, Itzhak; Labovitz, Arthur J.; Lang, Roberto M.; Mathew, Joseph; Moir, W. Stuart; Nagueh, Sherif F.; Pearlman, Alan S.; Perez, Julio E.; Porter, Thomas R.; Rosenbloom, Judy; Strachan, G. Monet; Thanigaraj, Srihari; Wei, Kevin; Woo, Anna; Yu, Eric H C; Zoghbi, William A.

    In: Journal of the American Society of Echocardiography, Vol. 21, No. 11, 11.2008, p. 1179-1201.

    Research output: Contribution to journalArticle

    Mulvagh, SL, Rakowski, H, Vannan, MA, Abdelmoneim, SS, Becher, H, Bierig, SM, Burns, PN, Castello, R, Coon, PD, Hagen, ME, Jollis, JG, Kimball, TR, Kitzman, DW, Kronzon, I, Labovitz, AJ, Lang, RM, Mathew, J, Moir, WS, Nagueh, SF, Pearlman, AS, Perez, JE, Porter, TR, Rosenbloom, J, Strachan, GM, Thanigaraj, S, Wei, K, Woo, A, Yu, EHC & Zoghbi, WA 2008, 'American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography', Journal of the American Society of Echocardiography, vol. 21, no. 11, pp. 1179-1201. https://doi.org/10.1016/j.echo.2008.09.009
    Mulvagh, Sharon L. ; Rakowski, Harry ; Vannan, Mani A. ; Abdelmoneim, Sahar S. ; Becher, Harald ; Bierig, S. Michelle ; Burns, Peter N. ; Castello, Ramon ; Coon, Patrick D. ; Hagen, Mary E. ; Jollis, James G. ; Kimball, Thomas R. ; Kitzman, Dalane W. ; Kronzon, Itzhak ; Labovitz, Arthur J. ; Lang, Roberto M. ; Mathew, Joseph ; Moir, W. Stuart ; Nagueh, Sherif F. ; Pearlman, Alan S. ; Perez, Julio E. ; Porter, Thomas R. ; Rosenbloom, Judy ; Strachan, G. Monet ; Thanigaraj, Srihari ; Wei, Kevin ; Woo, Anna ; Yu, Eric H C ; Zoghbi, William A. / American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. In: Journal of the American Society of Echocardiography. 2008 ; Vol. 21, No. 11. pp. 1179-1201.
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Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. 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    TY - JOUR

    T1 - American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography

    AU - Mulvagh, Sharon L.

    AU - Rakowski, Harry

    AU - Vannan, Mani A.

    AU - Abdelmoneim, Sahar S.

    AU - Becher, Harald

    AU - Bierig, S. Michelle

    AU - Burns, Peter N.

    AU - Castello, Ramon

    AU - Coon, Patrick D.

    AU - Hagen, Mary E.

    AU - Jollis, James G.

    AU - Kimball, Thomas R.

    AU - Kitzman, Dalane W.

    AU - Kronzon, Itzhak

    AU - Labovitz, Arthur J.

    AU - Lang, Roberto M.

    AU - Mathew, Joseph

    AU - Moir, W. Stuart

    AU - Nagueh, Sherif F.

    AU - Pearlman, Alan S.

    AU - Perez, Julio E.

    AU - Porter, Thomas R.

    AU - Rosenbloom, Judy

    AU - Strachan, G. Monet

    AU - Thanigaraj, Srihari

    AU - Wei, Kevin

    AU - Woo, Anna

    AU - Yu, Eric H C

    AU - Zoghbi, William A.

    PY - 2008/11

    Y1 - 2008/11

    N2 - Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

    AB - Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

    KW - Cardiac imaging

    KW - Contrast echocardiography

    KW - Contrast microbubbles

    KW - Coronary artery disease

    KW - Echocardiography

    KW - Endocardial border definition

    KW - Left ventricular ejection fraction

    KW - Left ventricular opacification

    KW - Myocardial contrast echocardiography

    KW - Myocardial perfusion imaging

    KW - Power Doppler imaging

    KW - Real-time contrast echocardiography

    KW - Stress echocardiography

    KW - Ultrasound contrast agents

    KW - Wall motion analysis

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