Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen

Amir Mor, Reshef Tal, Shoshana Haberman, Sandra Mccalla, Mohamad Irani, Jaqueline Perlman, David Seifer, Howard Minkoff

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

OBJECTIVE:: To estimate whether alpha-fetoprotein (AFP) can be used to distinguish amniotic fluid absorbed in sanitary pads from other similarly absorbed substances (semen, urine, and normal vaginal discharge). METHODS:: A prospective cohort study. Urine and amniotic fluid specimens were collected from 52 pregnant women admitted for labor. Semen specimens were collected from 17 men undergoing infertility evaluation. Alpha-fetoprotein concentrations were measured directly from urine, amniotic fluid, and semen and from pads instilled with samples from these specimens. Alpha-fetoprotein concentrations were also measured from pads absorbed with normal vaginal discharge collected from 27 pregnant women. RESULTS:: Alpha-fetoprotein levels in amniotic fluid (245.38±21.03 ng/mL, n=52) were significantly higher than those measured in maternal urine (0.84±0.17 ng/mL, n=52, P

Original languageEnglish (US)
Pages (from-to)448-452
Number of pages5
JournalObstetrics and Gynecology
Volume125
Issue number2
DOIs
StatePublished - Feb 6 2015
Externally publishedYes

Fingerprint

Vaginal Discharge
alpha-Fetoproteins
Amniotic Fluid
Semen
Urine
Pregnant Women
Infertility
Cohort Studies
Mothers
Prospective Studies

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Medicine(all)

Cite this

Mor, A., Tal, R., Haberman, S., Mccalla, S., Irani, M., Perlman, J., ... Minkoff, H. (2015). Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen. Obstetrics and Gynecology, 125(2), 448-452. https://doi.org/10.1097/AOG.0000000000000635

Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen. / Mor, Amir; Tal, Reshef; Haberman, Shoshana; Mccalla, Sandra; Irani, Mohamad; Perlman, Jaqueline; Seifer, David; Minkoff, Howard.

In: Obstetrics and Gynecology, Vol. 125, No. 2, 06.02.2015, p. 448-452.

Research output: Contribution to journalArticle

Mor, A, Tal, R, Haberman, S, Mccalla, S, Irani, M, Perlman, J, Seifer, D & Minkoff, H 2015, 'Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen', Obstetrics and Gynecology, vol. 125, no. 2, pp. 448-452. https://doi.org/10.1097/AOG.0000000000000635
Mor, Amir ; Tal, Reshef ; Haberman, Shoshana ; Mccalla, Sandra ; Irani, Mohamad ; Perlman, Jaqueline ; Seifer, David ; Minkoff, Howard. / Alpha-fetoprotein as a tool to distinguish amniotic fluid from urine, vaginal discharge, and semen. In: Obstetrics and Gynecology. 2015 ; Vol. 125, No. 2. pp. 448-452.
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AU - Seifer, David

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