Allergic contact dermatitis to two antioxidants in latex gloves: 4,4′-thiobis(6-tert-butyl-meta-cresol) (Lowinox 44S36) and butylhydroxyanisole: Allergen alternatives for glove-allergic patients

Phoebe Rich, Mary Lou Belozer, Patti Norris, Frances J. Storrs

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Allergic contact dermatitis developed on the hands and/or face of two patients after exposure to latex examination gloves. Both patients were patch test negative to the usual rubber allergens, but both had a positive patch test reaction to 4,4′-thiobis(6-tert-butyl-m-cresol) (Lowinox 44S36). Patient 2 was also patch test positive to butylhydroxyanisole. The patients were tested with other gloves, to find gloves that they could safely use. Glove manufacturers were queried to ascertain the occurrence of Lowinox 44S36 and butylhydroxyanisole in different brands of latex and vinyl examination gloves. A list of gloves and their associated allergens was generated and is provided to assist dermatologists in helping patients choose gloves free of specific allergens.

Original languageEnglish (US)
Pages (from-to)37-43
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume24
Issue number1
DOIs
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Dermatology

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