Advances in quantitative proteomics using stable isotope tags.

Mark Flory, Timothy J. Griffin, Daniel Martin, Ruedi Aebersold

Research output: Contribution to journalReview article

70 Citations (Scopus)

Abstract

A great deal of current biological and clinical research is directed at the interpretation of the information contained in the human genome sequence in terms of the structure, function and control of biological systems and processes. Proteomics, the systematic analysis of proteins, is becoming a critical component in this endeavor because proteomic measurements are carried out directly on proteins--the catalysts and effectors of essentially all biological functions. To detect changes in protein profiles that might provide important diagnostic or functional insights, proteomic analyses necessarily have to be quantitative. This article summarizes recent technological advances in quantitative proteomics.

Original languageEnglish (US)
JournalTrends in biotechnology
Volume20
Issue number12 Suppl
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Isotopes
Proteomics
Proteins
Biological Phenomena
Human Genome
Biological systems
Genes
Catalysts
Research

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Flory, M., Griffin, T. J., Martin, D., & Aebersold, R. (2002). Advances in quantitative proteomics using stable isotope tags. Trends in biotechnology, 20(12 Suppl).

Advances in quantitative proteomics using stable isotope tags. / Flory, Mark; Griffin, Timothy J.; Martin, Daniel; Aebersold, Ruedi.

In: Trends in biotechnology, Vol. 20, No. 12 Suppl, 01.01.2002.

Research output: Contribution to journalReview article

Flory, M, Griffin, TJ, Martin, D & Aebersold, R 2002, 'Advances in quantitative proteomics using stable isotope tags.', Trends in biotechnology, vol. 20, no. 12 Suppl.
Flory M, Griffin TJ, Martin D, Aebersold R. Advances in quantitative proteomics using stable isotope tags. Trends in biotechnology. 2002 Jan 1;20(12 Suppl).
Flory, Mark ; Griffin, Timothy J. ; Martin, Daniel ; Aebersold, Ruedi. / Advances in quantitative proteomics using stable isotope tags. In: Trends in biotechnology. 2002 ; Vol. 20, No. 12 Suppl.
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