Adult T-cell leukemia/lymphoma in a patient from Romania: A case report and review of the literature

Nicole Fett, Jawed Siddiqui, Caleb H. Creswell, Dahua Zhang, Rita Lloyd, Gary S. Wood

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Adult T-cell leukemia/lymphoma (ATLL) is a rare malignancy caused by human T-cell leukemia virus-1. ATLL is endemic to Japan, and to date, there are only four case reports of patients from Romania who have developed ATLL. Here, we describe a woman living in Madison, Wisconsin, originally from Romania, who presented with an atypical papulosquamous eruption and was ultimately diagnosed with smoldering ATLL. Narrow-band ultraviolet-B (UV-B) therapy and mid-potency topical steroids resulted in skin clearing for approximately 5 months after diagnosis; however, she subsequently relapsed with disease refractory to both narrow band UV-B and psoralen plus ultraviolet A (PUV-A), progressed to acute ATLL and expired secondary to complications.

Original languageEnglish (US)
Pages (from-to)32-37
Number of pages6
JournalJournal of Cutaneous Pathology
Volume35
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 2008
Externally publishedYes

Fingerprint

Adult T Cell Leukemia Lymphoma
Romania
Ultraviolet Therapy
Deltaretrovirus
Ficusin
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Japan
Steroids
Skin
Neoplasms

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

Cite this

Adult T-cell leukemia/lymphoma in a patient from Romania : A case report and review of the literature. / Fett, Nicole; Siddiqui, Jawed; Creswell, Caleb H.; Zhang, Dahua; Lloyd, Rita; Wood, Gary S.

In: Journal of Cutaneous Pathology, Vol. 35, No. SUPPL. 1, 10.2008, p. 32-37.

Research output: Contribution to journalArticle

Fett, Nicole ; Siddiqui, Jawed ; Creswell, Caleb H. ; Zhang, Dahua ; Lloyd, Rita ; Wood, Gary S. / Adult T-cell leukemia/lymphoma in a patient from Romania : A case report and review of the literature. In: Journal of Cutaneous Pathology. 2008 ; Vol. 35, No. SUPPL. 1. pp. 32-37.
@article{09e4a4a76cef4c4b8b02930777e07844,
title = "Adult T-cell leukemia/lymphoma in a patient from Romania: A case report and review of the literature",
abstract = "Adult T-cell leukemia/lymphoma (ATLL) is a rare malignancy caused by human T-cell leukemia virus-1. ATLL is endemic to Japan, and to date, there are only four case reports of patients from Romania who have developed ATLL. Here, we describe a woman living in Madison, Wisconsin, originally from Romania, who presented with an atypical papulosquamous eruption and was ultimately diagnosed with smoldering ATLL. Narrow-band ultraviolet-B (UV-B) therapy and mid-potency topical steroids resulted in skin clearing for approximately 5 months after diagnosis; however, she subsequently relapsed with disease refractory to both narrow band UV-B and psoralen plus ultraviolet A (PUV-A), progressed to acute ATLL and expired secondary to complications.",
author = "Nicole Fett and Jawed Siddiqui and Creswell, {Caleb H.} and Dahua Zhang and Rita Lloyd and Wood, {Gary S.}",
year = "2008",
month = "10",
doi = "10.1111/j.1600-0560.2007.00962.x",
language = "English (US)",
volume = "35",
pages = "32--37",
journal = "Journal of Cutaneous Pathology",
issn = "0303-6987",
publisher = "Wiley-Blackwell",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Adult T-cell leukemia/lymphoma in a patient from Romania

T2 - A case report and review of the literature

AU - Fett, Nicole

AU - Siddiqui, Jawed

AU - Creswell, Caleb H.

AU - Zhang, Dahua

AU - Lloyd, Rita

AU - Wood, Gary S.

PY - 2008/10

Y1 - 2008/10

N2 - Adult T-cell leukemia/lymphoma (ATLL) is a rare malignancy caused by human T-cell leukemia virus-1. ATLL is endemic to Japan, and to date, there are only four case reports of patients from Romania who have developed ATLL. Here, we describe a woman living in Madison, Wisconsin, originally from Romania, who presented with an atypical papulosquamous eruption and was ultimately diagnosed with smoldering ATLL. Narrow-band ultraviolet-B (UV-B) therapy and mid-potency topical steroids resulted in skin clearing for approximately 5 months after diagnosis; however, she subsequently relapsed with disease refractory to both narrow band UV-B and psoralen plus ultraviolet A (PUV-A), progressed to acute ATLL and expired secondary to complications.

AB - Adult T-cell leukemia/lymphoma (ATLL) is a rare malignancy caused by human T-cell leukemia virus-1. ATLL is endemic to Japan, and to date, there are only four case reports of patients from Romania who have developed ATLL. Here, we describe a woman living in Madison, Wisconsin, originally from Romania, who presented with an atypical papulosquamous eruption and was ultimately diagnosed with smoldering ATLL. Narrow-band ultraviolet-B (UV-B) therapy and mid-potency topical steroids resulted in skin clearing for approximately 5 months after diagnosis; however, she subsequently relapsed with disease refractory to both narrow band UV-B and psoralen plus ultraviolet A (PUV-A), progressed to acute ATLL and expired secondary to complications.

UR - http://www.scopus.com/inward/record.url?scp=50849133295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=50849133295&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0560.2007.00962.x

DO - 10.1111/j.1600-0560.2007.00962.x

M3 - Article

C2 - 18544058

AN - SCOPUS:50849133295

VL - 35

SP - 32

EP - 37

JO - Journal of Cutaneous Pathology

JF - Journal of Cutaneous Pathology

SN - 0303-6987

IS - SUPPL. 1

ER -