Adeno-associated virus finds its disease

David W. Russell, Markus Grompe

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Adeno-associated virus (AAV) vectors have been widely adopted for use in gene therapy. A new study raises concerns regarding this approach, reporting that chromosomal insertions of AAV serotype 2 seem to activate proto-oncogenes in human hepatocellular carcinoma.

Original languageEnglish (US)
Pages (from-to)1104-1105
Number of pages2
JournalNature Genetics
Volume47
Issue number10
DOIs
StatePublished - Sep 29 2015

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Dependovirus
Proto-Oncogenes
Genetic Therapy
Hepatocellular Carcinoma
Serogroup

ASJC Scopus subject areas

  • Genetics

Cite this

Adeno-associated virus finds its disease. / Russell, David W.; Grompe, Markus.

In: Nature Genetics, Vol. 47, No. 10, 29.09.2015, p. 1104-1105.

Research output: Contribution to journalArticle

Russell, David W. ; Grompe, Markus. / Adeno-associated virus finds its disease. In: Nature Genetics. 2015 ; Vol. 47, No. 10. pp. 1104-1105.
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