Adeno-associated virus finds its disease

David W. Russell, Markus Grompe

Research output: Contribution to journalShort survey

19 Scopus citations

Abstract

Adeno-associated virus (AAV) vectors have been widely adopted for use in gene therapy. A new study raises concerns regarding this approach, reporting that chromosomal insertions of AAV serotype 2 seem to activate proto-oncogenes in human hepatocellular carcinoma.

Original languageEnglish (US)
Pages (from-to)1104-1105
Number of pages2
JournalNature genetics
Volume47
Issue number10
DOIs
StatePublished - Sep 29 2015

ASJC Scopus subject areas

  • Genetics

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