Acoustical modulation of electrically evoked otoacoustic emission in intact gerbil cochlea

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In order to study the interaction between mechanical-electrical and electrical-mechanical transductions of outer hair cells (OHCs) in vivo, we observed the acoustically induced changes in the electrically evoked otoacoustic emission (EEOAE). One pole of a bipolar electrode was placed in the round window niche and the other pole on the surface of the first cochlear turn in the gerbil. A microphone and a speaker were used to monitor the EEOAE and to deliver an acoustical tone, respectively. It was found that a high sound level acoustical tone enhanced the EEOAE fine structure at frequencies below the acoustical frequency, and suppressed the overall level of the EEOAE at frequencies above the acoustical frequency. In addition, the EEOAE at frequencies approximately one half octave lower than the acoustical frequencies were relatively more enhanced or showed relatively less suppression than at other frequencies. The amplitudes of these changes had a positive relationship with acoustical tone levels. Furosemide eliminated the acoustically caused EEOAE change indicating that the acoustically caused change in the EEOAE is a phenomenon of the normal cochlea. One possible mechanism for the results is that the electrically and acoustically evoked basilar membrane (BM) vibrations interact at the EEOAE generation site and change the local mechanical and electrical properties. The second possible mechanism is that the acoustical stimulus creates an impedance discontinuity at its characteristic frequency location leading to a change in the reflected electrically evoked traveling wave, which may enhance or suppress the EEOAE by the vector summation of two waves.

Original languageEnglish (US)
Pages (from-to)7-16
Number of pages10
JournalHearing Research
Volume120
Issue number1-2
DOIs
StatePublished - Jun 1998

Fingerprint

Gerbillinae
Cochlea
Outer Auditory Hair Cells
Basilar Membrane
Furosemide
Vibration
Electric Impedance
Electrodes

Keywords

  • Cochlea
  • Cochlear amplifier
  • Electrical stimulation
  • Gerbil
  • Otoacoustic emission

ASJC Scopus subject areas

  • Sensory Systems

Cite this

Acoustical modulation of electrically evoked otoacoustic emission in intact gerbil cochlea. / Ren, Tianying; Nuttall, Alfred.

In: Hearing Research, Vol. 120, No. 1-2, 06.1998, p. 7-16.

Research output: Contribution to journalArticle

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