ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use

Deepak L. Bhatt, James Scheiman, Neena S. Abraham, Elliott M. Antman, Francis K L Chan, Curt D. Furberg, David A. Johnson, Kenneth W. Mahaffey, Eamonn M. Quigley, Robert A. Harrington, Eric R. Bates, Charles R. Bridges, Mark J. Eisenberg, Victor A. Ferrari, Mark A. Hlatky, Sanjay Kaul, Jonathan Lindner, David J. Moliterno, Debabrata Mukherjee, Richard S. SchofieldRobert S. Rosenson, James H. Stein, Howard H. Weitz, Deborah J. Wesley

Research output: Contribution to journalArticle

116 Citations (Scopus)

Abstract

In appropriate patients oral antiplatelet therapy decreases ischemic risks, but this therapy may increase bleeding complications. Of the major bleeding that occurs, the largest proportion is due to GI hemorrhage. Concomitant use of NSAIDs further raises the risk of GI bleeding. Gastroprotection strategies consist of use of PPIs in patients at high risk of GI bleeding and eradication of H. pylori in patients with a history of ulcers. Communication between cardiologists, gastroenterologists, and primary care physicians is critical to weigh the ischemic and bleeding risks in an individual patient who needs antiplatelet therapy but who is at risk for or develops significant GI bleeding.

Original languageEnglish (US)
Pages (from-to)2890-2907
Number of pages18
JournalAmerican Journal of Gastroenterology
Volume103
Issue number11
DOIs
StatePublished - Nov 2008
Externally publishedYes

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Non-Steroidal Anti-Inflammatory Agents
Consensus
Hemorrhage
Therapeutics
Pylorus
Primary Care Physicians
Ulcer
Communication

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Bhatt, D. L., Scheiman, J., Abraham, N. S., Antman, E. M., Chan, F. K. L., Furberg, C. D., ... Wesley, D. J. (2008). ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. American Journal of Gastroenterology, 103(11), 2890-2907. https://doi.org/10.1111/j.1572-0241.2008.02216.x

ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. / Bhatt, Deepak L.; Scheiman, James; Abraham, Neena S.; Antman, Elliott M.; Chan, Francis K L; Furberg, Curt D.; Johnson, David A.; Mahaffey, Kenneth W.; Quigley, Eamonn M.; Harrington, Robert A.; Bates, Eric R.; Bridges, Charles R.; Eisenberg, Mark J.; Ferrari, Victor A.; Hlatky, Mark A.; Kaul, Sanjay; Lindner, Jonathan; Moliterno, David J.; Mukherjee, Debabrata; Schofield, Richard S.; Rosenson, Robert S.; Stein, James H.; Weitz, Howard H.; Wesley, Deborah J.

In: American Journal of Gastroenterology, Vol. 103, No. 11, 11.2008, p. 2890-2907.

Research output: Contribution to journalArticle

Bhatt, DL, Scheiman, J, Abraham, NS, Antman, EM, Chan, FKL, Furberg, CD, Johnson, DA, Mahaffey, KW, Quigley, EM, Harrington, RA, Bates, ER, Bridges, CR, Eisenberg, MJ, Ferrari, VA, Hlatky, MA, Kaul, S, Lindner, J, Moliterno, DJ, Mukherjee, D, Schofield, RS, Rosenson, RS, Stein, JH, Weitz, HH & Wesley, DJ 2008, 'ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use', American Journal of Gastroenterology, vol. 103, no. 11, pp. 2890-2907. https://doi.org/10.1111/j.1572-0241.2008.02216.x
Bhatt, Deepak L. ; Scheiman, James ; Abraham, Neena S. ; Antman, Elliott M. ; Chan, Francis K L ; Furberg, Curt D. ; Johnson, David A. ; Mahaffey, Kenneth W. ; Quigley, Eamonn M. ; Harrington, Robert A. ; Bates, Eric R. ; Bridges, Charles R. ; Eisenberg, Mark J. ; Ferrari, Victor A. ; Hlatky, Mark A. ; Kaul, Sanjay ; Lindner, Jonathan ; Moliterno, David J. ; Mukherjee, Debabrata ; Schofield, Richard S. ; Rosenson, Robert S. ; Stein, James H. ; Weitz, Howard H. ; Wesley, Deborah J. / ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. In: American Journal of Gastroenterology. 2008 ; Vol. 103, No. 11. pp. 2890-2907.
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